Description

  • Product name

    Recombinant Human HS3ST1 protein
  • Purity

    > 90 % SDS-PAGE.
    ab171694 is purified using conventional chromatography techniques
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSRPAELGQ QELLRKAGTL QDDVRDGVAP NGSAQQLPQT IIIGVRKGGT RALLEMLSLH PDVAAAENEV HFFDWEEHYS HGLGWYLSQM PFSWPHQLTV EKTPAYFTSP KVPERVYSMN PSIRLLLILR DPSERVLSDY TQVFYNHMQK HKPYPSIEEF LVRDGRLNVD YKALNRSLYH VHMQNWLRFF PLRHIHIVDG DRLIRDPFPE IQKVERFLKL SPQINASNFY FNKTKGFYCL RDSGRDRCLH ESKGRAHPQV DPKLLNKLHE YFHEPNKKFF ELVGRTFDWH
    • Predicted molecular weight

      36 kDa including tags
    • Amino acids

      21 to 307
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab171694 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.03% DTT, 0.32% Tris HCl, 40% Glycerol, 1.17% Sodium chloride

General Info

  • Alternative names

    • 3-OST-1
    • 3OST
    • 3OST1
    • EC 2.8.2.23
    • h3 OST 1
    • h3-OST-1
    • Heparan sulfate (glucosamine) 3 O sulfotransferase 1
    • Heparan sulfate 3 O sulfotransferase 1
    • Heparan sulfate 3-O-sulfotransferase 1
    • Heparan sulfate D glucosaminyl 3 O sulfotransferase 1
    • Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1
    • Heparan sulfate glucosamine 3-O-sulfotransferase 1
    • Heparin glucosamine 3 O sulfotransferase
    • HS3S1_HUMAN
    • HS3ST 1
    • Hs3st1
    see all
  • Function

    Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site.
  • Tissue specificity

    Highly expressed in the brain and kidney and weakly expressed in the heart, lung and placenta.
  • Sequence similarities

    Belongs to the sulfotransferase 1 family.
  • Cellular localization

    Golgi apparatus lumen.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab171694 (3µg).

References

ab171694 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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