For the best experience on the Abcam website please upgrade to a modern browser such as
Full length protein
Amino Acid Sequence
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
< 0.100 Eu/µg
>95% by SDS-PAGE .
Concentration information loading...
Stability and Storage
Shipped on Dry Ice. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Constituents: 0.24% Tris, 0.88% Sodium chloride Supplied as a 0.2 µM filtered solution
3 alpha HSD1
3-alpha-hydroxysteroid dehydrogenase type I
Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
Belongs to the aldo/keto reductase family.
The N-terminus is blocked.
Information by UniProt
SDS-PAGE - Recombinant Human HSD3a protein (ab172176)
SDS-PAGE gel of ab172176 under reduced (lane 1) and non reduced (lane 2) conditions
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"