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    recombinant-human-hsp70-protein-ab48997.pdf

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Signal Transduction Protein Trafficking Chaperones Heat Shock Proteins
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Recombinant Human Hsp70 protein (ab48997)

  • Datasheet
  • SDS
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SDS-PAGE - Recombinant Human Hsp70 protein (ab48997)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 95% SDS-PAGE
    • Suitable for: SDS-PAGE

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    Description

    • Product name

      Recombinant Human Hsp70 protein
      See all Hsp70 proteins and peptides
    • Purity

      > 95 % SDS-PAGE.
      This protein was purified by using conventional chromatography techniques.
    • Expression system

      Escherichia coli
    • Protein length

      Full length protein
    • Animal free

      No
    • Nature

      Recombinant
      • Species

        Human
      • Sequence

        MGSSHHHHHH SSGLVPRGSH MAKAAAIGID LGTTYSCVGV FQHGKVEIIA NDQGNRTTPS YVAFTDTERL IGDAAKNQVA LNPQNTVFDA KRLIGRKFGD PVVQSDMKHW PFQVINDGDK PKVQVSYKGD TKAFYPEEIS SMVLTKMKEI AEAYLGYPVT NAVITVPAYF NDSQRQATKD AGVIAGLNVL RIINEPTAAA IAYGLDRTGK GERNVLIFDL GGGTFDVSIL TIDDGIFEVK ATAGDTHLGG EDFDNRLVNH FVEEFKRKHK KDISQNKRAV RRLRTACERA KRTLSSSTQA SLEIDSLFEG IDFYTSITRA RFEELCSDLF RSTLEPVEKA LRDAKLDKAQ IHDLVLVGGS TRIPKVQKLL QDFFNGRDLN KSINPDEAVA YGAAVQAAIL MGDKSENVQD LLLLDVAPLS LGLETAGGVM TALIKRNSTI PTKQTQIFTT YSDNQPGVLI QVYEGERAMT KDNNLLGRFE LSGIPPAPRG VPQIEVTFDI DANGILNVTA TDKSTGKANK ITITNDKGRL SKEEIERMVQ EAEKYKAEDE VQRERVSAKN ALESYAFNMK SAVEDEGLKG KISEADKKKV LDKCQEVISW LDANTLAEKD EFEHKRKELE QVCNPIISGL YQGAGGPGPG GFGAQGPKGG SGSGPTIEEV D

    Associated products

    • Related Products

      • HRP Anti-6X His tag® antibody (ab1187)
      • Anti-Hsp70 antibody (ab124208)
      • HRP Anti-6X His tag® antibody (ab1269)
      • Anti-Hsp70 antibody [5A5] (ab2787)
      • Anti-Hsp70 antibody [EP1007Y] (ab45133)
      • Anti-Hsp70 antibody [C92F3A-5] (ab47455)
      • Anti-6X His tag® antibody [4D11] (ab5000)
      • Anti-6X His tag® antibody (ab9108)

    Specifications

    Our Abpromise guarantee covers the use of ab48997 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

      pH: 7.50
      Constituents: 0.0308% DTT, 0.242% Tris

    General Info

    • Alternative names

      • DnaK type molecular chaperone HSP70 1
      • Epididymis secretory protein Li 103
      • FLJ54303
      • FLJ54370
      • FLJ54392
      • FLJ54408
      • FLJ75127
      • Heat shock 70 kDa protein 1
      • Heat shock 70 kDa protein 1/2
      • Heat shock 70 kDa protein 1A
      • Heat shock 70 kDa protein 1A/1B
      • Heat shock 70kDa protein 1B
      • Heat shock induced protein
      • HEL S 103
      • HSP70 1
      • HSP70 1A
      • HSP70 1B
      • HSP70 2
      • HSP70-1
      • HSP70-1/HSP70-2
      • HSP70-1A
      • HSP70-2
      • HSP70.1
      • HSP70.1/HSP70.2
      • HSP71_HUMAN
      • HSP72
      • HSPA1
      • HSPA1A
      • HSPA1B
      see all
    • Relevance

      Function: In cooperation with other chaperones, the Hsp70 family stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell. Tissue specificity: HSPA1B is testis-specific.
    • Cellular localization

      Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

    Images

    • SDS-PAGE - Recombinant Human Hsp70 protein (ab48997)
      SDS-PAGE - Recombinant Human Hsp70 protein (ab48997)
      ab48997 run on a 15% SDS PAGE gel with molecular weight markers.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (0)

    Publishing research using ab48997? Please let us know so that we can cite the reference in this datasheet.

    ab48997 has not yet been referenced specifically in any publications.

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