Product nameRecombinant Human Iba1 protein
See all Iba1 proteins and peptides
Protein lengthFull length protein
Amino Acid Sequence
SequenceMSQTRDLQGGKAFGLLKAQQEERLDEINKQFLDDPKYSSDEDLPSKLEGF KEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGET FSYPDFLRMMLGKRSAILKMILMYEEKAREKEKPTGPPAKKAISELP
Molecular weight18 kDa including tags
Amino acids1 to 147
TagsHis tag C-Terminus
- Anti-Iba1 antibody (ab105464)
- Anti-Iba1 antibody (ab108539)
- Anti-Iba1 antibody (ab153696)
- Anti-Iba1 antibody [1022-5] (ab15690)
- Anti-6X His tag® antibody [HIS.H8] (ab18184)
- Anti-Iba1 antibody (ab48004)
- Anti-6X His tag® antibody [4D11] (ab5000)
- Anti-Iba1 antibody (ab5076)
- Anti-6X His tag® antibody - ChIP Grade (ab9108)
Our Abpromise guarantee covers the use of ab173043 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Endotoxin level1.000 Eu/µg
Purity>95% by SDS-PAGE .
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on Dry Ice. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Constituent: 100% PBS
Supplied as a 0.2 µm Ø filtered solution.
- AIF 1
FunctionActin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Tissue specificityDetected in T-lymphocytes and peripheral blood mononuclear cells.
Sequence similaritiesContains 2 EF-hand domains.
modificationsPhosphorylated on serine residues.
Cellular localizationCytoplasm > cytoskeleton. Cell projection > ruffle membrane. Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
- Information by UniProt
ab173043 has not yet been referenced specifically in any publications.