The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.242% Tris, 50% Glycerol
Antigen identified by monoclonal antibody BB2
Cell surface glycoprotein P3.58
Human rhinovirus receptor
Intercellular adhesion molecule 1
intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
Major group rhinovirus receptor
Surface antigen of activated B cells, BB2
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Belongs to the immunoglobulin superfamily. ICAM family. Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.