Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag N-Terminus, T7 tag N-Terminus
- Suitable for: SDS-PAGE
Product nameRecombinant Human ICAM2 protein
See all ICAM2 proteins and peptides
Purity> 90 % SDS-PAGE.
ab134869 was expressed in E. coli as inclusion bodies, refolded using a temperature shift inclusion body refolding technology and chromatographically purified.
Expression systemEscherichia coli
Protein lengthProtein fragment
SequenceMASMTGGQQMGRGHHHHHHGNLYFQGGEFELKVFEVHVRPKKLAVEPKGS LEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHF TCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLD SLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAV LDLMSRGGNIFHKHSAPKMLEIYEPVSDSQ
Predicted molecular weight26 kDa including tags
Amino acids25 to 223
TagsHis tag N-Terminus , T7 tag N-Terminus
Our Abpromise guarantee covers the use of ab134869 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Constituent: 0.32% Tris HCl
contains NaCl, EDTA, KCl, arginine, DTT and glycerol.
- CD102 antigen
- ICAM 2
RelevanceICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin like C2 type domains, and bind to the leukocyte adhesion LFA1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA1 dependent cell adhesion. It mediates adhesive interactions important for antigen specific immune response, NK cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
Cellular localizationMembrane; Single-pass type I membrane protein
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab134869 has been referenced in 1 publication.
- Swaim CD et al. Extracellular ISG15 Signals Cytokine Secretion through the LFA-1 Integrin Receptor. Mol Cell 68:581-590.e5 (2017). PubMed: 29100055