Overview

  • Product name

    Recombinant Human ID2 protein (denatured)
    See all ID2 proteins and peptides
  • Protein length

    Full length protein
  • Description

    Recombinant Human ID2 protein

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MKAFSPVRSV RKNSLSDHSL GISRSKTPVD DPMSLLYNMN DCYSKLKELV PSIPQNKKVS KMEILQHVID YILDLQIALD SHPTIVSLHH QRPGQNQASR TPLTTLNTDI SILSLQASEF PSELMSNDSK ALCG
    • Molecular weight

      17 kDa including tags
    • Amino acids

      1 to 134
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab140586 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity

    > 85 % SDS-PAGE.

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 2.4% Urea, 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names

    • bHLHb26
    • Cell growth inhibiting gene 8
    • class B basic helix loop helix protein 26
    • Class B basic helix-loop-helix protein 26
    • DNA binding protein inhibitor ID 2
    • DNA binding protein inhibitor ID2
    • DNA-binding protein inhibitor ID-2
    • GIG 8
    • GIG8
    • Helix loop helix protein ID2
    • ID2
    • ID2_HUMAN
    • ID2A
    • ID2H
    • Inhibitor of differentiation 2
    • Inhibitor of DNA binding 2
    • Inhibitor of DNA binding 2, dominant negative helix loop helix protein
    • MGC26389
    see all
  • Function

    ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-2 may be an inhibitor of tissue-specific gene expression.
  • Tissue specificity

    Highly expressed in early fetal tissues, including those of the central nervous system.
  • Sequence similarities

    Contains 1 basic helix-loop-helix (bHLH) domain.
  • Developmental stage

    Found in most early fetal tissues but not in the corresponding mature tissues.
  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab140586 (3µg).

References

ab140586 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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