Description

  • Product name

    Recombinant Human IGLL1 protein (denatured)
  • Purity

    > 85 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSLLRPTAA SQSRALGPGA PGGSSRSSLR SRWGRFLLQR GSWTGPRCWP RGFQSKHNSV THVFGSGTQL TVLSQPKATP SVTLFPPSSE ELQANKATLV CLMNDFYPGI LTVTWKADGT PITQGVEMTT PSKQSNNKYA ASSYLSLTPE QWRSRRSYSC QVMHEGSTVE KTVAPAECS
    • Predicted molecular weight

      22 kDa including tags
    • Amino acids

      38 to 213
    • Tags

      His tag N-Terminus
  • Description

    Recombinant Human IGLL1 protein

Specifications

Our Abpromise guarantee covers the use of ab140547 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 2.4% Urea, 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names

    • 14.1
    • AGM2
    • CD179 antigen-like family member B
    • CD179b
    • CD179b antigen
    • Ig lambda 5
    • Ig lambda-5
    • IGL1
    • IGL5
    • IGLJ14.1
    • IGLL
    • Igll1
    • IGLL1_HUMAN
    • IGO
    • IGVPB
    • Immunoglobulin lambda like polypeptide 1 precursor
    • Immunoglobulin lambda-like polypeptide 1
    • Immunoglobulin omega polypeptide
    • Immunoglobulin omega polypeptide chain
    • Immunoglobulin related protein 14.1
    • Immunoglobulin-related protein 14.1
    • Lambda5
    • Pre B lymphocyte specific protein 2
    • VPREB2
    see all
  • Function

    Critical for B-cell development.
  • Tissue specificity

    Expressed only in pre-B-cells and a special B-cell line (which is surface Ig negative).
  • Involvement in disease

    Defects in IGLL1 are the cause of agammaglobulinemia type 2 (AGM2) [MIM:613500]. It is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development. Affected individuals develop severe infections in the first years of life.
  • Sequence similarities

    Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab140547 (3µg).

References

ab140547 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab140547.
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