Recombinant Human IKZF5 protein (ab163827)

Submit a review Submit a question

Description

  • Product name

    Recombinant Human IKZF5 protein

  • Expression system

    Wheat germ

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      GEKKPEPLDFVKDFQEYLTQQTHHVNMISGSVSGDKEAEALQGAGTDGDQ NGLDHPSVEVSLDENSGMLVDGFERTFDGKLKCRYCNYASKGTARLIEH

    • Amino acids

      2 to 100

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab163827 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid

  • Additional notes

     

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • DKFZp781B0249
    • FLJ22973
    • IKAROS family zinc finger 5 (Pegasus)
    • Ikaros family zinc finger protein 5
    • IKZF5
    • IKZF5_HUMAN
    • PEGASUS
    • Zinc finger protein Pegasus
    • Zinc finger protein subfamily 1A 5
    • Zinc finger transcription factor Pegasus
    • ZNFN1A5
    see all

  • Function

    DNA-binding protein that binds to the 5'GNNTGTNG-3' core sequence. Transcriptional repressor.

  • Tissue specificity

    Expressed in brain, heart, skeletal muscle, kidney, and liver. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K562. Highly expressed in THP-1 and Mo7e-IL3 cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively.

  • Sequence similarities

    Belongs to the Ikaros C2H2-type zinc-finger protein family.
    Contains 5 C2H2-type zinc fingers.

  • Domain

    The N-terminal zinc fingers are involved in sequence-specific DNA binding and heterotypic associations with other family members.
    C-terminal zinc fingers mediate homodimerization.

  • Cellular localization

    Nucleus.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human IKZF5 protein (ab163827)
    SDS-PAGE - Recombinant Human IKZF5 protein (ab163827)
    ab163827 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References

Publishing research using ab163827? Please let us know so that we can cite the reference in this datasheet.

ab163827 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Show All Reviews Q&A
Submit a review Submit a question

There are currently no Customer reviews or Questions for ab163827.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com