Recombinant Human IKZF5 protein (ab163827)

Our Abpromise guarantee covers the use of ab163827 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Alternative names
- DKFZp781B0249
- FLJ22973
- IKAROS family zinc finger 5 (Pegasus)
- Ikaros family zinc finger protein 5
- IKZF5
- IKZF5_HUMAN
- PEGASUS
- Zinc finger protein Pegasus
- Zinc finger protein subfamily 1A 5
- Zinc finger transcription factor Pegasus
- ZNFN1A5
see all
Function

DNA-binding protein that binds to the 5'GNNTGTNG-3' core sequence. Transcriptional repressor.
Tissue specificity

Expressed in brain, heart, skeletal muscle, kidney, and liver. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K562. Highly expressed in THP-1 and Mo7e-IL3 cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively.
Sequence similarities

Belongs to the Ikaros C2H2-type zinc-finger protein family.
Contains 5 C2H2-type zinc fingers.
Domain

The N-terminal zinc fingers are involved in sequence-specific DNA binding and heterotypic associations with other family members.
C-terminal zinc fingers mediate homodimerization.
Cellular localization

Nucleus.
Target information above from: UniProt accession Q9H5V7 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

SDS-PAGE - Recombinant Human IKZF5 protein (ab163827)

ab163827 on a 12.5% SDS-PAGE stained with Coomassie Blue.

ab163827 has not yet been referenced specifically in any publications.

Publishing research using ab163827? Please let us know so that we can cite the reference in this datasheet.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"