Key features and details
- Expression system: Pichia pastoris
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Active: Yes
- Suitable for: HPLC, SDS-PAGE, Functional Studies
Product nameRecombinant human IL-11 protein
See all IL-11 proteins and peptides
Biological activityED50 is less than 0.2 ng/ml as determined by the dose-dependent stimulation of murine 7TD1 proliferation. Specific Activity of 8.0 x 106 IU/ mg.
Purity> 95 % SDS-PAGE.
Greater than 95% as determined by RP-HPLC and reducing SDS-PAGE.
Endotoxin level< 1.000 Eu/µg
Expression systemPichia pastoris
Protein lengthFull length protein
SequenceGPPPGPPRVSPDPRAELDSTVLLTRSLLADTRQLAAQLRDKFPADGDHNL DSLPTLAMSAGALGALQLPGVLTRLRADLLSYLRHVQWLRRAGGSSLKTL EPELGTLQARLDRLLRRLQLLMSRLALPQPPPDPPAPPLAPPSSAWGGIR AAHAILGGLHLTLDWAVRGLLLLKTRL
Predicted molecular weight19 kDa
Amino acids23 to 199
Our Abpromise guarantee covers the use of ab151817 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -80°C.
Constituents: 97% PBS, 2% Glycine
This product is an active protein and may elicit a biological response in vivo, handle with caution.
ReconstitutionAlways centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Adipogenesis inhibitory factor
- IL 11
FunctionDirectly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.
Sequence similaritiesBelongs to the IL-6 superfamily.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab151817 has not yet been referenced specifically in any publications.