Bioactive grade

Recombinant human IL-11 protein (Animal Free) (ab222362)

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Description

  • Product name

    Recombinant human IL-11 protein (Animal Free)
    See all IL-11 proteins and peptides

  • Biological activity

    T11 cell proliferation: ED50 ≤2.5 ng/ml; ≥ 4.0 x 105 units/mg.

  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

    <=1.000 Eu/µg

  • Expression system

    Escherichia coli

  • Accession

    P20809

  • Protein length

    Full length protein

  • Animal free

    Yes

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MPGPPPGPPRVSPDPRAELDSTVLLTRSLLADTRQLAAQLRDKFPADGDH NLDSLPTLAMSAGALGALQLPGVLTRLRADLLSYLRHVQWLRRAGGSSLK TLEPELGTLQARLDRLLRRLQLLMSRLALPQPPPDPPAPPLAPPSSAWGG IRAAHAILGGLHLTLDWAVRGLLLLKTRL

    • Predicted molecular weight

      19 kDa

    • Amino acids

      22 to 199

    • Additional sequence information

      This product is the mature full length protein from aa 22 to 199. The signal peptide is not included.

Associated products

Specifications

Our Abpromise guarantee covers the use of ab222362 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C long term. Avoid freeze / thaw cycle.

    Constituent: 0.1% Trifluoroacetic acid

    Lyophilized from a sterile 0.2 micron filtered solution.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Centrifuge vial before opening. Suspend the product by gently pipetting sterile water down the sides of the vial to a final concentration of 0.1 mg/ml. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C. Avoid repeat freeze thaw. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.

General Info

  • Alternative names

    • Adipogenesis inhibitory factor
    • AGIF
    • IL 11
    • IL-11
    • Il11
    • IL11_HUMAN
    • Interleukin 11
    • Interleukin-11
    • Oprelvekin
    see all

  • Function

    Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.

  • Sequence similarities

    Belongs to the IL-6 superfamily.

  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • Functional Studies - Recombinant human IL-11 protein (Animal Free) (ab222362)
    Functional Studies - Recombinant human IL-11 protein (Animal Free) (ab222362)
    Functional analysis of ab222362
  • SDS-PAGE - Recombinant human IL-11 protein (Animal Free) (ab222362)
    SDS-PAGE - Recombinant human IL-11 protein (Animal Free) (ab222362)

     SDS PAGE analysis of ab222362 under non-reducing (-) and reducing (+) conditions. Stained with Coomassie Blue.

References

ab222362 has not yet been referenced specifically in any publications.

Publishing research using ab222362? Please let us know so that we can cite the reference in this datasheet.

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