Recombinant human IL-17A protein (Active) (ab256041)
- Datasheet
- References
- Protocols
Description
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Product name
Recombinant human IL-17A protein (Active)
See all IL-17A proteins and peptides -
Biological activity
Production of IL-6 from mouse NIH/3T3 cells. ≤10 ng/mL; ≥ 1.0 x 105 units/mg.
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Purity
> 95 % SDS-PAGE. -
Endotoxin level
< 1.000 Eu/µg -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MIVKAGITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYN RSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQE ILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVA -
Predicted molecular weight
16 kDa -
Amino acids
21 to 155
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Specifications
Our Abpromise guarantee covers the use of ab256041 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
Functional Studies
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Form
Lyophilised -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at room temperature. Store at -20°C.
Constituent: 0.1% Trifluoroacetic acid
0.2 micron filteredThis product is an active protein and may elicit a biological response in vivo, handle with caution.
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ReconstitutionReconstitute in sterile water to 0.1 mg/ml, Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.
General Info
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Alternative names
- CTLA 8
- CTLA-8
- CTLA8
see all -
Function
Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts. -
Tissue specificity
Restricted to activated memory T-cells. -
Sequence similarities
Belongs to the IL-17 family. -
Post-translational
modificationsFound both in glycosylated and nonglycosylated forms. -
Cellular localization
Secreted. - Information by UniProt
Images
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SDS-PAGE analysis of ab256041 (1μg) under non-reducing (Lane 1) and reducing (Lane 2) conditions. ab256041 is a homodimer with predicted to have a MW of 31.3 kDa.
4-20% Tris-Glycine gel. Coomassie Blue staining.
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Functional analysis of ab256041.
References
ab256041 has not yet been referenced specifically in any publications.