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    recombinant-human-il-2-receptor-alpha-protein-fc-chimera-his-tag-ab223005.pdf

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Immunology Adaptive Immunity T Cells CD
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Recombinant Human IL-2 Receptor alpha protein (Fc Chimera His Tag) (ab223005)

  • Datasheet
  • SDS
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SDS-PAGE - Recombinant Human IL-2 Receptor alpha protein (Fc Chimera His Tag) (ab223005)

    Key features and details

    • Expression system: Baculovirus infected insect cells
    • Purity: > 90% SDS-PAGE
    • Endotoxin level: < 1.000 Eu/µg
    • Tags: His tag C-Terminus
    • Suitable for: SDS-PAGE

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    Description

    • Product name

      Recombinant Human IL-2 Receptor alpha protein (Fc Chimera His Tag)
      See all IL-2 Receptor alpha proteins and peptides
    • Purity

      > 90 % SDS-PAGE.
      Affinity purified
    • Endotoxin level

      < 1.000 Eu/µg
    • Expression system

      Baculovirus infected insect cells
    • Accession

      P01589
    • Protein length

      Protein fragment
    • Animal free

      No
    • Nature

      Recombinant
      • Species

        Human
      • Sequence

        ADPELCDDDPPEIPHATFKAMAYKEGTMLNCECKRGFRRIKSGSLYMLCT GNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQ ASLPGHCREPPPWENEATERIYHFVVGQMVYYQCVQGYRALHRGPAESVC KMTHGKTRWTQPQLICTGEMETSQFPGEEKPQASPEGRPESETSCLVTTT DFQIQTEMAATMETSIFTTEYQLEPKSCDKTHTCPPCPAPELLGGPSVFL FPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPR EEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQ PREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYK TTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLS LSPGKHHHHHH
      • Predicted molecular weight

        52 kDa including tags
      • Amino acids

        22 to 240
      • Tags

        His tag C-Terminus
      • Additional sequence information

        Extracellular domain fused to hIgGHis-tag at C-terminus (NP_000408).

    Associated products

    • Related Products

      • Anti-IL-2 Receptor alpha antibody [EPR6452] (ab128955)
      • Anti-6X His tag® antibody [HIS.H8] (ab18184)
      • Anti-IL-2 Receptor alpha antibody [EPR6452] - BSA and Azide free (ab215378)
      • Anti-6X His tag® antibody [4D11] (ab5000)
      • Anti-6X His tag® antibody (ab9108)

    Specifications

    Our Abpromise guarantee covers the use of ab223005 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituents: PBS, 10% Glycerol (glycerin, glycerine)

    General Info

    • Alternative names

      • Interleukin 2 receptor alpha chain
      • CD25
      • CD25 antigen
      • IDDM10
      • IL 2 receptor alpha subunit
      • IL-2 receptor subunit alpha
      • IL-2-RA
      • IL-2R subunit alpha
      • IL2 RA
      • IL2 Receptor alpha
      • IL2-RA
      • IL2R
      • IL2R, alpha chain
      • IL2RA
      • IL2RA_HUMAN
      • IMD41
      • Interleukin 2 receptor
      • Interleukin 2 receptor alpha
      • Interleukin-2 receptor subunit alpha
      • p55
      • t-cell growth factor receptor
      • TAC
      • TAC antigen
      • TCGFR
      see all
    • Function

      Receptor for interleukin-2.
    • Involvement in disease

      Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
    • Sequence similarities

      Contains 2 Sushi (CCP/SCR) domains.
    • Cellular localization

      Membrane.
    • Target information above from: UniProt accession P01589 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human IL-2 Receptor alpha protein (Fc Chimera His Tag) (ab223005)
      SDS-PAGE - Recombinant Human IL-2 Receptor alpha protein (Fc Chimera His Tag) (ab223005)

      15% SDS-PAGE analysis of 3 µg ab223005.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (0)

    Publishing research using ab223005? Please let us know so that we can cite the reference in this datasheet.

    ab223005 has not yet been referenced specifically in any publications.

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