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Immunology Innate Immunity Cytokines Interleukins
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Bioactive grade

Recombinant human IL-20R2 protein (Fc Chimera) (ab179978)

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SDS-PAGE - Recombinant human IL-20R2 protein (Fc Chimera) (ab179978)

    Key features and details

    • Expression system: HEK 293 cells
    • Purity: > 90% SDS-PAGE
    • Endotoxin level: < 1.000 Eu/µg
    • Active: Yes
    • Suitable for: SDS-PAGE, Functional Studies

    Description

    • Product name

      Recombinant human IL-20R2 protein (Fc Chimera)
      See all IL-20R2 proteins and peptides
    • Biological activity

      Measured by its binding ability in a functional ELISA.
      When Recombinant Human IL19 protein is present at 0.2 µg/mL, the concentration of ab179978 that produces 50% of the optimal binding response is approximately 5-50 ng/ml.

    • Purity

      > 90 % SDS-PAGE.

    • Endotoxin level

      < 1.000 Eu/µg
    • Expression system

      HEK 293 cells
    • Accession

      Q6UXL0
    • Protein length

      Protein fragment
    • Animal free

      No
    • Nature

      Recombinant
      • Species

        Human
      • Sequence

        DEVAILPAPQNLSVLSTNMKHLLMWSPVIAPGETVYYSVEYQGEYESLYT SHIWIPSSWCSLTEGPECDVTDDITATVPYNLRVRATLGSQTSAWSILKH PFNRNSTILTRPGMEITKDGFHLVIELEDLGPQFEFLVAYWRREPGAEEH VKMVRSGGIPVHLETMEPGAAYCVKAQTFVKAIGRYSAFSQTECVEVQGE A
      • Predicted molecular weight

        49 kDa including tags
      • Amino acids

        30 to 230
      • Additional sequence information

        Accession AAH63696. Fused with Fc fragment of Human IgG1 at the C-terminus.

    Associated products

    • Related Products

      • Anti-IL-20R2 antibody (ab124332)

    Specifications

    Our Abpromise guarantee covers the use of ab179978 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      Functional Studies

    • Form

      Lyophilized
    • Additional notes

      Protein previously labeled as IL20RB.

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at 4°C prior to reconstitution. Store at -80°C. Reconstitute for long term storage.

      pH: 7.4
      Constituents: 0.75% Glycine, 0.61% Tris, 5% Trehalose

      This product is an active protein and may elicit a biological response in vivo, handle with caution.

    • Reconstitution
      Reconstitute with sterile deionized water to a concentration of 200 µg/ml.

    General Info

    • Alternative names

      • DIRS1
      • Fibronectin type III domain containing 6
      • FNDC6
      • I20RB_HUMAN
      • IL 20R beta
      • IL 20R2
      • IL-20 receptor subunit beta
      • IL-20R-beta
      • IL-20R2
      • IL-20RB
      • IL20RB
      • Interleukin 20 receptor beta
      • Interleukin 20 receptor beta chain precursor
      • Interleukin 20 receptor II
      • Interleukin-20 receptor subunit beta
      • MGC34923
      see all
    • Function

      The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.
    • Tissue specificity

      Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.
    • Sequence similarities

      Belongs to the type II cytokine receptor family.
      Contains 2 fibronectin type-III domains.
    • Cellular localization

      Membrane.
    • Target information above from: UniProt accession Q6UXL0 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    • SDS-PAGE - Recombinant human IL-20R2 protein (Fc Chimera) (ab179978)
      SDS-PAGE - Recombinant human IL-20R2 protein (Fc Chimera) (ab179978)

      SDS-PAGE analysis of reduced ab179978 stained overnight with Coomassie Blue.

      Lane 1: DTT-reduced protein.

      Lane 2: Non-reduced protein.

      As a result of glycosylation, DTT-reduced Protein migrates as 50 kDa and non-reduced protein migrates as 100 kDa.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab179978? Please let us know so that we can cite the reference in this datasheet.

    ab179978 has not yet been referenced specifically in any publications.

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