Bioactive grade

Recombinant human IL-20R2 protein (Fc Chimera) (ab179978)

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Description

  • Product name

    Recombinant human IL-20R2 protein (Fc Chimera)
    See all IL-20R2 proteins and peptides

  • Biological activity

    Measured by its binding ability in a functional ELISA.
    When Recombinant Human IL19 protein is present at 0.2 µg/mL, the concentration of ab179978 that produces 50% of the optimal binding response is approximately 5-50 ng/ml.

  • Purity

    > 90 % SDS-PAGE.

  • Endotoxin level

    < 1.000 Eu/µg

  • Expression system

    HEK 293 cells

  • Accession

    Q6UXL0

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      DEVAILPAPQNLSVLSTNMKHLLMWSPVIAPGETVYYSVEYQGEYESLYT SHIWIPSSWCSLTEGPECDVTDDITATVPYNLRVRATLGSQTSAWSILKH PFNRNSTILTRPGMEITKDGFHLVIELEDLGPQFEFLVAYWRREPGAEEH VKMVRSGGIPVHLETMEPGAAYCVKAQTFVKAIGRYSAFSQTECVEVQGE A

    • Predicted molecular weight

      49 kDa including tags

    • Amino acids

      30 to 230

    • Additional sequence information

      Accession AAH63696. Fused with Fc fragment of Human IgG1 at the C-terminus.

Associated products

Specifications

Our Abpromise guarantee covers the use of ab179978 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Form

    Lyophilised

  • Additional notes

    Protein previously labeled as IL20RB.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at 4°C prior to reconstitution. Store at -80°C. Reconstitute for long term storage.

    pH: 7.00
    Constituents: 0.75% Glycine, 0.61% Tris, 5% Trehalose

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • DIRS1
    • Fibronectin type III domain containing 6
    • FNDC6
    • I20RB_HUMAN
    • IL 20R beta
    • IL 20R2
    • IL-20 receptor subunit beta
    • IL-20R-beta
    • IL-20R2
    • IL-20RB
    • IL20RB
    • Interleukin 20 receptor beta
    • Interleukin 20 receptor beta chain precursor
    • Interleukin 20 receptor II
    • Interleukin-20 receptor subunit beta
    • MGC34923
    see all

  • Function

    The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.

  • Tissue specificity

    Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.

  • Sequence similarities

    Belongs to the type II cytokine receptor family.
    Contains 2 fibronectin type-III domains.

  • Cellular localization

    Membrane.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant human IL-20R2 protein (Fc Chimera) (ab179978)
    SDS-PAGE - Recombinant human IL-20R2 protein (Fc Chimera) (ab179978)

    SDS-PAGE analysis of reduced ab179978 stained overnight with Coomassie Blue.

    Lane 1: DTT-reduced protein.

    Lane 2: Non-reduced protein.

    As a result of glycosylation, DTT-reduced Protein migrates as 50 kDa and non-reduced protein migrates as 100 kDa.

References

ab179978 has not yet been referenced specifically in any publications.

Publishing research using ab179978? Please let us know so that we can cite the reference in this datasheet.

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