Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MAPISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACI

Specifications

Our Abpromise guarantee covers the use of ab49821 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Endotoxin level
    < 0.100 Eu/µg
  • Purity
    > 95 % SDS-PAGE.
    Greater than 97% by SDS-PAGE.
  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Endotoxin level is less than 0.1 ng per µg (1EU/µg).

  • Reconstitution
    Reconstitute in water to a concentration of 0.1-1.0 mg/ml.

General Info

  • Alternative names
    • Cytokine Zcyto18
    • IL 10 related T cell derived inducible factor
    • IL 21
    • IL 22
    • IL D110
    • IL TIF
    • IL-10-related T-cell-derived-inducible factor
    • IL-22
    • IL-TIF
    • IL21
    • Il22
    • IL22_HUMAN
    • ILD110
    • ILTIF
    • Interleukin 10 related T cell derived inducible factor
    • interleukin 21
    • Interleukin 22
    • Interleukin-22
    • MGC79382
    • MGC79384
    • TIFa
    • TIFIL 23
    • TIFIL23
    • UNQ3099/PRO10096
    • zcyto18
    see all
  • Function
    Cytokine that contributes to the inflammatory response in vivo.
  • Sequence similarities
    Belongs to the IL-10 family.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab49821 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

1-3 of 3 Abreviews or Q&A

Answer

Product ab49821, full length IL-22, is the protein without the signal peptide. In general, very few, if any, of the proteins we offer include the signal peptide. That is the case for all our IL22, IFNg, and GMCSF proteins; none include the signal peptides.

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Answer

Thank you for contacting us.

Please check the following link http://www.uniprot.org/uniprot/Q96PD4; IL24 is synonym for IL17F as given in uniprot protein database however the uniprot ID and GeneID for both proteins are different. I am sorry I am unsure why the name used as synonym but different IDS. You may need to search this in literature. The following are the useful links;

http://www.uniprot.org/uniprot/Q13007

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11009

http://www.uniprot.org/uniprot/Q96PD4

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=112744

The IL17F protein we have are

https://www.abcam.com/IL17F-protein-Human-ab78475.html
https://www.abcam.com/IL17F-protein-Active-ab119722.html
https://www.abcam.com/IL17F-protein-ab50157.html (this is homo-dimer)
https://www.abcam.com/IL17F-protein-Active-ab85600.html

The protein ab40044 is not IL17F it is actualy IL17A or IL17; http://www.uniprot.org/uniprot/Q16552

I have asked lab to confirm, why the signal peptide amino acids are included. I will send you the details soon.

These products are developed by our collaborators and they are from different suppliers which is why the price is different.

Finally, we can provide the product at ab82830 at 0.5mg/ml which is the lower limit at which the product can be used with conjugation kits.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Use our products? Submit an Abreview. Earn rewards!
https://www.abcam.com/abreviews

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Answer

Thank you for your phone call.

The protein ab82830 is a monomer; it not homodimer. The amino acid sequence can be found at http://www.uniprot.org with protein ID Q16552.

We unfortunately will not be able to supply this protein as FITC conjugated or PerCP conjugated product. I am sorry our lab will not be able to conjugate these on custom basis. I however have requested lab if they can provide this protein in higher concentration so that the conjugation kits can be used.

We will not be able to provide ab49821, IL22 protein as His tagged.

The IL24 protein we have is ab131696.

I will let you know further when I receive a reply form lab.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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