Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Molecular weight

      33 kDa
    • Amino acids

      91 to 378
    • Tags

      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127351 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names

    • Class I cytokine receptor
    • CRL
    • CRL 3
    • CRL3
    • Cytokine receptor like 3
    • Cytokine receptor-like 3
    • GLM R
    • GLM-R
    • GLMR
    • Gp130 like monocyte receptor
    • GP130 like receptor
    • Gp130-like monocyte receptor
    • Gp130-like receptor
    • GPL
    • HGLM R
    • HGLM-R
    • HGLMR
    • IL 31 receptor subunit alpha
    • IL 31R subunit alpha
    • IL 31RA
    • IL-31 receptor subunit alpha
    • IL-31R subunit alpha
    • IL-31R-alpha
    • IL-31RA
    • IL31 receptor subunit alpha
    • IL31R subunit alpha
    • IL31R_HUMAN
    • IL31RA
    • Interleukin 31 receptor A
    • interleukin 31 receptor subunit alpha
    • Interleukin-31 receptor subunit alpha
    • MGC125346
    • PLCA 2
    • PLCA2
    • PRO21384
    • Soluble type I cytokine receptor CRL3
    • ZcytoR17
    see all
  • Function

    Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity.
  • Tissue specificity

    Expressed at low levels in testis, ovary, brain, prostate, placenta, thymus, bone marrow, trachea and skin. Detected in all of the myelomonocytic lineage. Expressed in CD14-and CD56-positive blood cells and by macrophages (at protein level).
  • Sequence similarities

    Belongs to the type I cytokine receptor family. Type 2 subfamily.
    Contains 5 fibronectin type-III domains.
  • Post-translational
    modifications

    N-glycosylated.
  • Cellular localization

    Cell membrane.
  • Information by UniProt

References

ab127351 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab127351.
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