Description

  • Product name

    Recombinant Human IL-3RB protein (His tag)
  • Purity

    > 95 % SDS-PAGE.
    ab211309 was purified using conventional chromatography techniques.
  • Endotoxin level

    < 1.000 Eu/µg
  • Expression system

    Insect cells
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      WERSLAGAEE TIPLQTLRCY NDYTSHITCR WADTQDAQRL VNVTLIRRVN EDLLEPVSCD LSDDMPWSAC PHPRCVPRRC VIPCQSFVVT DVDYFSFQPD RPLGTRLTVT LTQHVQPPEP RDLQISTDQD HFLLTWSVAL GSPQSHWLSP GDLEFEVVYK RLQDSWEDAA ILLSNTSQAT LGPEHLMPSS TYVARVRTRL APGSRLSGRP SKWSPEVCWD SQPGDEAQPQ NLECFFDGAA VLSCSWEVRK EVASSVSFGL FYKPSPDAGE EECSPVLREG LGSLHTRHHC QIPVPDPATH GQYIVSVQPR RAEKHIKSSV NIQMAPPSLN VTKDGDSYSL RWETMKMRYE HIDHTFEIQY RKDTATWKDS KTETLQNAHS MALPALEPST RYWARVRVRT SRTGYNGIWS EWSEARSWDT ESVLPMWLEH HHHHH
    • Predicted molecular weight

      50 kDa including tags
    • Amino acids

      17 to 443
    • Tags

      His tag C-Terminus
    • Additional sequence information

      NP_000386. Extracellular domain

Specifications

Our Abpromise guarantee covers the use of ab211309 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.4
    Constituents: 90% PBS, 10% Glycerol

General Info

  • Alternative names

    • Beta-C
    • CD131
    • CDw131
    • Colony stimulating factor 2 receptor beta
    • Colony stimulating factor 2 receptor beta low affinity (granulocyte macrophage)
    • Common beta chain
    • Csf2rb
    • Cytokine receptor common beta chain
    • Cytokine receptor common beta chain precursor (CDw131 antigen)
    • Cytokine receptor common subunit beta
    • GM CSF/IL 3/IL 5 receptor common beta chain
    • GM-CSF/IL-3/IL-5 receptor common beta subunit
    • granulocyte-macrophage colony-stimulating factor receptor, beta
    • IL3RB
    • IL3RB_HUMAN
    • IL5RB
    • Interleukin 3 receptor, beta
    • Interleukin 3 receptor/granulocyte macrophage colony stimulating factor 3 receptor beta (high affinity)
    • Interleukin 5 receptor, beta
    • SMDP5
    • stimulating factor 3 receptor, beta (high affinity)
    see all
  • Function

    High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
  • Sequence similarities

    Belongs to the type I cytokine receptor family. Type 4 subfamily.
    Contains 2 fibronectin type-III domains.
  • Domain

    The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • Cellular localization

    Membrane.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab211309 (3μg). 40-57kDa (SDS-PAGE under reducing conditions).

References

ab211309 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab211309.
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