Bioactive grade

Recombinant human IL36 gamma/IL-1F9 protein (ab138902)

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Description

  • Product name

    Recombinant human IL36 gamma/IL-1F9 protein
    See all IL36 gamma/IL-1F9 proteins and peptides

  • Biological activity

    Measured by its ability to induce IL8 production by Human PBMCs.

  • Purity

    > 95 % SDS-PAGE.
    Purity: > 95% by SDS-PAGE gel and HPLC analyses.

  • Endotoxin level

    < 0.100 Eu/µg

  • Expression system

    Escherichia coli

  • Accession

    Q9NZH8

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      SMCKPITGTI NDLNQQVWTL QGQNLVAVPR SDSVTPVTVA VITCKYPEAL EQGRGDPIYL GIQNPEMCLY CEKVGEQPTL QLKEQKIMDL YGQPEPVKPF LFYRAKTGRT STLESVAFPD WFIASSKRDQ PIILTSELGK SYNTAFELNI ND

    • Predicted molecular weight

      17 kDa

    • Amino acids

      18 to 169

Specifications

Our Abpromise guarantee covers the use of ab138902 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

    HPLC

  • Form

    Lyophilised

  • Additional notes

    Measured by its ability to induce IL8 production by Human PBMCs.

    Previously labelled as IL36 gamma. 

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 7.00
    Constituents: 0.14% Sodium phosphate, 0.29% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA).

General Info

  • Alternative names

    • IL 1 epsilon
    • IL 1 related protein 2
    • IL 1(EPSILON)
    • IL 1F9
    • IL 1H1
    • IL 1RP2
    • IL-1 epsilon
    • IL-1-related protein 2
    • IL-1F9
    • IL-1H1
    • IL-1RP2
    • IL1E
    • Il1f9
    • IL1F9_HUMAN
    • IL1H1
    • IL1RP2
    • IL36 gamma
    • IL36G
    • Interleukin 1 epsilon
    • Interleukin 1 family member 9
    • Interleukin 1 homolog 1
    • Interleukin 1 related protein 2
    • Interleukin 36 gamma
    • Interleukin-1 epsilon
    • Interleukin-1 family member 9
    • Interleukin-1 homolog 1
    see all

  • Function

    Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response.

  • Tissue specificity

    Highly expressed in tissues containing epithelial cells: skin, lung, stomach and esophagus. In skin is expressed only in keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Up-regulated in lesional psoriasis skin.

  • Sequence similarities

    Belongs to the IL-1 family.

  • Cellular localization

    Secreted.
  • Information by UniProt

References

ab138902 has not yet been referenced specifically in any publications.

Publishing research using ab138902? Please let us know so that we can cite the reference in this datasheet.

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