Description

  • Product name

    Recombinant Human IL3RA/CD123 protein (His tag)
    See all IL3RA/CD123 proteins and peptides
  • Purity

    > 90 % SDS-PAGE.
    ab277400 was purified by using conventional chromatography techniques.
  • Endotoxin level

    < 1.000 Eu/µg
  • Expression system

    Baculovirus infected insect cells
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      ADLKEDPNPP ITNLRMKAKA QQLTWDLNRN VTDIECVKDA DYSMPAVNNS YCQFGAISLC EVTNYTVRVA NPPFSTWILF PENSGKPWAG AENLTCWIHD VDFLSCSWAV GPGAPADVQY DLYLNVANRR QQYECLHYKT DAQGTRIGCR FDDISRLSSG SQSSHILVRG RSAAFGIPCT DKFVVFSQIE ILTPPNMTAK CNKTHSFMHW KMRSHFNRKF RYELQIQKRM QPVITEQVRD RTSFQLLNPG TYTVQIRARE RVYEFLSAWS TPQRFECDQE EGANTRAWRH HHHHH
    • Predicted molecular weight

      34 kDa including tags
    • Amino acids

      20 to 305
    • Tags

      His tag C-Terminus
    • Additional sequence information

      NP_002174

Specifications

Our Abpromise guarantee covers the use of ab227400 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

    Previously labelled as IL3RA. 

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.4
    Constituents: PBS, 10% Glycerol

General Info

  • Alternative names

    • CD123
    • CD123 antigen
    • hIL 3Ra
    • hIL-3Ra
    • hIL3Ra
    • IL 3 receptor alpha SP2 isoform
    • IL 3R alpha
    • IL-3 receptor subunit alpha
    • IL-3R subunit alpha
    • IL-3R-alpha
    • IL-3RA
    • IL3 Receptor alpha
    • IL3R
    • Il3ra
    • IL3RA_HUMAN
    • IL3RAX
    • IL3RAY
    • IL3RX
    • IL3RY
    • Interleukin 3 receptor alpha chain
    • Interleukin 3 receptor, alpha
    • Interleukin 3 receptor, alpha (low affinity)
    • Interleukin-3 Receptor alpha
    • Interleukin-3 receptor subunit alpha
    • Interleukin3 receptor
    • Interleukin3 receptor, Y-chromosomal
    see all
  • Function

    This is a receptor for interleukin-3.
  • Sequence similarities

    Belongs to the type I cytokine receptor family. Type 5 subfamily.
  • Domain

    The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • Cellular localization

    Membrane.
  • Information by UniProt

Images

  • 15% SDS-PAGE - 3 µg Recombinant Human IL3RA / CD123 protein (His tag) (ab227400).

    Migrates at 40-57 kDa under reducing conditions.

References

ab227400 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab227400.
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