Recombinant Human INCA protein (ab171673)

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SDS-PAGE - Recombinant Human INCA protein (ab171673)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 95% SDS-PAGE
    • Tags: His tag N-Terminus
    • Suitable for: SDS-PAGE, MS

    Description

    • Product name

      Recombinant Human INCA protein

    • Purity

      > 95 % SDS-PAGE.
      ab171673 was purified using conventional chromatography techniques.

    • Expression system

      Escherichia coli

    • Accession

      Q5XLA6

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MGSSHHHHHHSSGLVPRGSHMGSMADKVLKEKRKQFIRSVGEGTINGLLG ELLETRVLSQEEIEIVKCENATVMDKARALLDSVIRKGAPACQICITYIC EEDSHLAGTLGLSAGPTSGNHLTTQDSQIVLPS

      • Predicted molecular weight

        14 kDa including tags

      • Amino acids

        1 to 110

      • Tags

        His tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab171673 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      Mass Spectrometry

    • Mass spectrometry

      MALDI-TOF

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 8.00
      Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol (glycerin, glycerine), 0.88% Sodium chloride

    General Info

    • Alternative names

      • CAR17_HUMAN
      • CARD 17
      • CARD17
      • Caspase 1 inhibitor
      • Caspase recruitment domain containing protein 17
      • Caspase recruitment domain-containing protein 17
      • Caspase-1 inhibitor INCA
      • Caspase1 inhibitor
      • Inhibitory caspase recruitment domain (CARD) protein
      • Inhibitory caspase recruitment domain protein
      see all

    • Function

      Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.

    • Tissue specificity

      Ubiquitous.

    • Sequence similarities

      Contains 1 CARD domain.

    • Cellular localization

      Cytoplasm.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human INCA protein (ab171673)
      SDS-PAGE - Recombinant Human INCA protein (ab171673)
      15% SDS-PAGE analysis of ab171673 (3µg).

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab171673? Please let us know so that we can cite the reference in this datasheet.

    ab171673 has not yet been referenced specifically in any publications.

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