Recombinant Human INCA protein (ab171673)

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Description

  • Product name

    Recombinant Human INCA protein

  • Purity

    > 95 % SDS-PAGE.
    ab171673 was purified using conventional chromatography techniques.

  • Expression system

    Escherichia coli

  • Accession

    Q5XLA6

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MGSSHHHHHHSSGLVPRGSHMGSMADKVLKEKRKQFIRSVGEGTINGLLG ELLETRVLSQEEIEIVKCENATVMDKARALLDSVIRKGAPACQICITYIC EEDSHLAGTLGLSAGPTSGNHLTTQDSQIVLPS

    • Predicted molecular weight

      14 kDa including tags

    • Amino acids

      1 to 110

    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab171673 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol, 0.88% Sodium chloride

General Info

  • Alternative names

    • CAR17_HUMAN
    • CARD 17
    • CARD17
    • Caspase 1 inhibitor
    • Caspase recruitment domain containing protein 17
    • Caspase recruitment domain-containing protein 17
    • Caspase-1 inhibitor INCA
    • Caspase1 inhibitor
    • Inhibitory caspase recruitment domain (CARD) protein
    • Inhibitory caspase recruitment domain protein
    see all

  • Function

    Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.

  • Tissue specificity

    Ubiquitous.

  • Sequence similarities

    Contains 1 CARD domain.

  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human INCA protein (ab171673)
    SDS-PAGE - Recombinant Human INCA protein (ab171673)
    15% SDS-PAGE analysis of ab171673 (3µg).

References

ab171673 has not yet been referenced specifically in any publications.

Publishing research using ab171673? Please let us know so that we can cite the reference in this datasheet.

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