Recombinant human Indoleamine 2, 3-dioxygenase protein (Active) (ab216193)

Description

  • Product name

    Recombinant human Indoleamine 2, 3-dioxygenase protein (Active)
    See all Indoleamine 2, 3-dioxygenase proteins and peptides
  • Biological activity

    ab216193 activity was confirmed using an IDO1 inhibitor screening assay kit.

  • Purity

    > 90 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MHHHHHHAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAK HLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGK GHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLT YENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERD TLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLS DGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQD MRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRS YHLQIVTKYILIPASQQPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRST TE KSLLKEG
    • Predicted molecular weight

      46 kDa including tags
    • Amino acids

      2 to 403
    • Tags

      His tag N-Terminus
    • Additional sequence information

      Expressed in the presence of hemin.

Specifications

Our Abpromise guarantee covers the use of ab216193 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Form

    Liquid
  • Additional notes

    Storing diluted protein is not recommended, if necessary, use carrier protein (BSA 0.1 – 0.5%).

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 8
    Constituents: 20% Glycerol, 0.02% Potassium chloride, 0.64% Sodium chloride, 0.63% Tris HCl

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • 3-dioxygenase
    • I23O1_HUMAN
    • IDO
    • IDO 1
    • IDO-1
    • IDO1
    • INDO
    • indolamine 2,3 dioxygenase
    • Indole 2 3 dioxygenase
    • indoleamine 2 3 dioxygenase
    • indoleamine 2 3 dioxygenase 1
    • Indoleamine 2,3-dioxygenase 1
    • Indoleamine pyrrole 2 3 dioxygenase
    • Indoleamine-pyrrole 2
    see all
  • Function

    Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.
  • Pathway

    Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 1/2.
  • Sequence similarities

    Belongs to the indoleamine 2,3-dioxygenase family.
  • Information by UniProt

Images

  • Example of ab216193 enzyme activity test.

  • 4-20% SDS-PAGE Coomassie staining:


    3 µg ab216193

References

ab216193 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab216193.
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