Recombinant human Inhibin beta A protein (Active) (ab255808)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
Description
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Product name
Recombinant human Inhibin beta A protein (Active)
See all Inhibin beta A proteins and peptides -
Biological activity
Cytotoxicity of MPC-11 cells: ≤10 ng/mL; ≥ 1.0 x 105 units/mg
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Purity
> 95 % SDS-PAGE. -
Endotoxin level
< 1.000 Eu/µg -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
Yes -
Nature
Recombinant -
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Species
Human -
Sequence
MGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIA GTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQN IIKKDIQNMIVEECGCS -
Predicted molecular weight
13 kDa -
Amino acids
311 to 426 -
Additional sequence information
Full-length mature chain lacking the signal and propeptides. Sequence identical in mouse and rat.
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab255808 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
Functional Studies
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at Room Temperature. Store at -80°C. Avoid freeze / thaw cycle.
Constituent: 0.1% Trifluoroacetic acid
0.2 micron filteredThis product is an active protein and may elicit a biological response in vivo, handle with caution.
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ReconstitutionReconstitute in sterile water to 0.1 mg/ml. Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.
General Info
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Alternative names
- Activin beta-A chain
- EDF
- Erythroid differentiation factor
see all -
Function
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. -
Sequence similarities
Belongs to the TGF-beta family. -
Cellular localization
Secreted. - Information by UniProt
Images
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SDS-PAGE - Recombinant human Inhibin beta A protein (Active) (ab255808)
SDS-PAGE analysis of ab255808 (1μg) under reducing (+) and non-reducing (-) conditions.
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Functional Studies - Recombinant human Inhibin beta A protein (Active) (ab255808)Functional activity of ab255808.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab255808 has not yet been referenced specifically in any publications.