Bioactive grade

Recombinant human Inhibin beta A protein (Active) (ab255808)

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Description

  • Product name

    Recombinant human Inhibin beta A protein (Active)
    See all Inhibin beta A proteins and peptides

  • Biological activity

    Cytotoxicity of MPC-11 cells:  ≤10 ng/mL; ≥ 1.0 x 105 units/mg

  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

    < 1.000 Eu/µg

  • Expression system

    Escherichia coli

  • Accession

    P08476

  • Protein length

    Full length protein

  • Animal free

    Yes

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIA GTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQN IIKKDIQNMIVEECGCS

    • Predicted molecular weight

      13 kDa

    • Amino acids

      311 to 426

    • Additional sequence information

      Full-length mature chain lacking the signal and propeptides. Sequence identical in mouse and rat.

Specifications

Our Abpromise guarantee covers the use of ab255808 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at Room Temperature. Store at -80°C. Avoid freeze / thaw cycle.

    Constituent: 0.1% Trifluoroacetic acid

    0.2 micron filtered

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Reconstitute in sterile water to 0.1 mg/ml. Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

General Info

  • Alternative names

    • Activin beta-A chain
    • EDF
    • Erythroid differentiation factor
    • Erythroid differentiation protein
    • Follicle stimulating hormone releasing protein
    • FRP
    • FSH releasing protein
    • INHBA
    • INHBA_HUMAN
    • Inhibin beta A chain
    • Inhibin beta A subunit
    • Inhibin, beta 1
    • Inhibin, beta A (activin A, activin AB alpha polypeptide)
    see all

  • Function

    Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

  • Sequence similarities

    Belongs to the TGF-beta family.

  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant human Inhibin beta A protein (Active) (ab255808)
    SDS-PAGE - Recombinant human Inhibin beta A protein (Active) (ab255808)

    SDS-PAGE analysis of ab255808 (1μg) under reducing (+) and non-reducing (-) conditions.

  • Functional Studies - Recombinant human Inhibin beta A protein (Active) (ab255808)
    Functional Studies - Recombinant human Inhibin beta A protein (Active) (ab255808)

    Functional activity of ab255808.

References

ab255808 has not yet been referenced specifically in any publications.

Publishing research using ab255808? Please let us know so that we can cite the reference in this datasheet.

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