Overview

  • Product name
    Recombinant Human iNOS protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      133 kDa including tags
    • Amino acids
      2 to 1153
    • Tags
      His-DDDDK tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab135010 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Purity
    >95% by SDS-PAGE .

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.017% Potassium chloride, 0.06% DTT, 0.64% Tris HCl, 20% Glycerol, 0.65% Sodium chloride

General Info

  • Alternative names
    • HEP-NOS
    • Hepatocyte NOS
    • HEPNOS
    • inducible
    • Inducible nitric oxide synthase
    • Inducible NO synthase
    • Inducible NOS
    • iNOS
    • MAC NOS
    • Macrophage NOS
    • Nitric oxide synthase
    • Nitric oxide synthase 2 inducible
    • Nitric oxide synthase 2 inducible macrophage
    • nitric oxide synthase 2A (inducible, hepatocytes)
    • Nitric oxide synthase inducible
    • nitric oxide synthase, macrophage
    • NOS
    • NOS 2
    • Nos II
    • NOS type II
    • nos2
    • NOS2_HUMAN
    • NOS2A
    • NOS2A, Inducible, Hepatocyte
    • Peptidyl-cysteine S-nitrosylase NOS2
    see all
  • Function
    Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
  • Tissue specificity
    Expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not expressed in the platelets.
  • Sequence similarities
    Belongs to the NOS family.
    Contains 1 FAD-binding FR-type domain.
    Contains 1 flavodoxin-like domain.
  • Information by UniProt

Images

  • 10% SDS-PAGE analysis of ab135010 (1 μg), followed by Coomassie staining.
    Lane 1: ab135010
    Lane 2: MW marker

References

ab135010 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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