• Product name

    Recombinant human Insulin protein (Active)
    See all Insulin proteins and peptides
  • Purity

    > 98 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

  • Nature

    • Species

    • Predicted molecular weight

      6 kDa
    • Additional sequence information

      Gen ID: 3630


Our Abpromise guarantee covers the use of ab54126 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications


  • Form

  • Additional notes

    Endotoxin Level: <0.1 ng/ug

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Add 1% BSA for extra stability. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Endotoxin: Less than 0.1 ng/mg of Insulin

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Centrifuge the vial prior to opening. Reconstitute in 0.01 M HCl. The solution can then be diluted to other aqueous buffers.

General Info

  • Alternative names

    • IDDM
    • IDDM1
    • IDDM2
    • ILPR
    • ins
    • Insulin A chain
    • Insulin B chain
    • IRDN
    • MODY10
    • Preproinsulin
    • Proinsulin
    • Proinsulin precursor
    see all
  • Function

    Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
  • Involvement in disease

    Defects in INS are the cause of familial hyperproinsulinemia (FHPRI) [MIM:176730].
    Defects in INS are a cause of diabetes mellitus insulin-dependent type 2 (IDDM2) [MIM:125852]. IDDM2 is a multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
    Defects in INS are a cause of diabetes mellitus permanent neonatal (PNDM) [MIM:606176]. PNDM is a rare form of diabetes distinct from childhood-onset autoimmune diabetes mellitus type 1. It is characterized by insulin-requiring hyperglycemia that is diagnosed within the first months of life. Permanent neonatal diabetes requires lifelong therapy.
    Defects in INS are a cause of maturity-onset diabetes of the young type 10 (MODY10) [MIM:613370]. MODY10 is a form of diabetes that is characterized by an autosomal dominant mode of inheritance, onset in childhood or early adulthood (usually before 25 years of age), a primary defect in insulin secretion and frequent insulin-independence at the beginning of the disease.
  • Sequence similarities

    Belongs to the insulin family.
  • Cellular localization

  • Information by UniProt


  • 4-20% SDS-PAGE of ab54126, stained with Coomassie Blue.

    Lane 1: 2 ug

    Lane 2: 5 ug

    Lane 3: 10ug

    Predicted MW: 5.81 kDa



ab54126 has not yet been referenced specifically in any publications.

Customer reviews and Q&As


Thank you for contacting us. You can ask any questions to us we are happy to help. We can only guarantee these proteins acting as inducers in functional assays in human cells. These proteins are tested only with human cells. The RAT insulin 1, 2 and human insulin sequence is 83% similar so theoretically these proteins may induce cellular activities in Rat cells also. However we are unable to confirm it because we don’t have tested data of rat cells. If you would like to use these proteins with rat samples then let me know I will be happy to create a discount code for you. The discount code will give you, next purchase of 1 protein product free of charge. I would however also need the information of assay you would like to perform.  I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.  

Read More

For licensing inquiries, please contact

Sign up