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    recombinant-human-integrin-alpha-v-protein-tagged-ab114240.pdf

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Cardiovascular Angiogenesis Adhesion / ECM Integrins
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Recombinant Human Integrin alpha V protein (Tagged) (ab114240)

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SDS-PAGE - Recombinant Human Integrin alpha V protein (Tagged) (ab114240)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: ELISA, SDS-PAGE, WB

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    Description

    • Product name

      Recombinant Human Integrin alpha V protein (Tagged)
    • Expression system

      Wheat germ
    • Accession

      P06756
    • Protein length

      Full length protein
    • Animal free

      No
    • Nature

      Recombinant
      • Species

        Human
      • Sequence

        MAFPPRRRLR LGPRGLPLLL SGLLLPLCRA FNLDVDSPAE YSGPEGSYFG FAVDFFVPSA SSRMFLLVGA PKANTTQPGI VEGGQVLKCD WSSTRRCQPI EFDATGNRDY AKDDPLEFKS HQWFGASVRS KQDKILACAP LYHWRTEMKQ EREPVGTCFL QDGTKTVEYA PCRSQDIDAD GQGFCQGGFS IDFTKADRVL LGGPGSFYWQ GQLISDQVAE IVSKYDPNVY SIKYNNQLAT RTAQAIFDDS YLGYSVAVGD FNGDGIDDFV SGVPRAARTL GMVYIYDGKN MSSLYNFTGE QMAAYFGFSV AATDINGDDY ADVFIGAPLF MDRGSDGKLQ EVGQVSVSLQ RASGDFQTTK LNGFEVFARF GSAIAPLGDL DQDGFNDIAI AAPYGGEDKK GIVYIFNGRS TGLNAVPSQI LEGQWAARSM PPSFGYSMKG ATDIDKNGYP DLIVGAFGVD RAILYRARPV ITVNAGLEVY PSILNQDNKT CSLPGTALKV SCFNVRFCLK ADGKGVLPRK LNFQVELLLD KLKQKGAIRR ALFLYSRSPS HSKNMTISRG GLMQCEELIA YLRDESEFRD KLTPITIFME YRLDYRTAAD TTGLQPILNQ FTPANISRQA HILLDCGEDN VCKPKLEVSV DSDQKKIYIG DDNPLTLIVK AQNQGEGAYE AELIVSIPLQ ADFIGVVRNN EALARLSCAF KTENQTRQVV CDLGNPMKAG TQLLAGLRFS VHQQSEMDTS VKFDLQIQSS NLFDKVSPVV SHKVDLAVLA AVEIRGVSSP DHVFLPIPNW EHKENPETEE DVGPVVQHIY ELRNNGPSSF SKAMLHLQWP YKYNNNTLLY ILHYDIDGPM NCTSDMEINP LRIKISSLQT TEKNDTVAGQ GERDHLITKR DLALSEGDIH TLGCGVAQCL KIVCQVGRLD RGKSAILYVK SLLWTETFMN KENQNHSYSL KSSASFNVIE FPYKNLPIED ITNSTLVTTN VTWGIQPAPM PVPVWVIILA VLAGLLLLAV LVFVMYRMGF FKRVRPPQEE QEREQLQPHE NGEGNSET
      • Predicted molecular weight

        143 kDa including tags
      • Amino acids

        1 to 1048
      • Tags

        GST tag N-Terminus

    Associated products

    • Related Products

      • Anti-Integrin alpha V antibody [P2W7] (ab11470)
      • Anti-Integrin alpha V antibody [272-17E6] - BSA and Azide free (ab16821)
      • Anti-Integrin alpha V beta 3 antibody [27.1 (VNR-1)] (ab78289)

    Specifications

    Our Abpromise guarantee covers the use of ab114240 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      ELISA

      SDS-PAGE

      Western blot

    • Form

      Liquid
    • Additional notes

       

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.3% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • antigen identified by monoclonal antibody L230
      • CD 51
      • CD51
      • DKFZp686A08142
      • Integrin alpha five
      • integrin alpha V beta 3
      • Integrin alpha-5
      • integrin alpha-V
      • Integrin alpha-V light chain
      • integrin alphaVbeta3
      • integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
      • ITAV_HUMAN
      • ITGAV
      • MSK 8
      • Msk8
      • Vitronectin receptor subunit alpha
      • VNRA
      • VTNR
      see all
    • Function

      The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
    • Sequence similarities

      Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
    • Cellular localization

      Membrane.
    • Target information above from: UniProt accession P06756 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human Integrin alpha V protein (Tagged) (ab114240)
      SDS-PAGE - Recombinant Human Integrin alpha V protein (Tagged) (ab114240)

      12.5% SDS-PAGE showing ab114240 at approximately 143 kDa stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet download

      Download

    References (0)

    Publishing research using ab114240? Please let us know so that we can cite the reference in this datasheet.

    ab114240 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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