Recombinant human Interferon beta protein (Active) (ab71475)

Overview

Description

  • Nature
    Recombinant
  • Source
    CHO cells
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MSYNLLGFLQ RSSNFQCQKL LWQLNGRLEY CLKDRMNFDI PEEIKQLQQF QKEDAALTIY EMLQNIFAIF RQDSSSTGWN ETIVENLLAN VYHQINHLKT VLEEKLEKED FTRGKLMSSL HLKRYYGRIL HYLKAKEYSH CAWTIVRVEI LRNFYFINRL TGYLRN
    • Molecular weight
      20 kDa
    • Amino acids
      22 to 187
    • Additional sequence information
      Full length mature protein, minus the signal peptide.

Specifications

Our Abpromise guarantee covers the use of ab71475 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity

    Assay #1: Determined by its ability to induce STAT1/STAT2 activation in Human COLO 205 ISRE LUC reporter cells.

    Assay #2: Determined by a cytotoxicity assay using human TF-1 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

  • Applications

    SDS-PAGE

    Functional Studies

    HPLC

  • Endotoxin level
    < 1.000 Eu/µg
  • Purity
    >= 95 % SDS-PAGE.
    >= 95% HPLC analyses. Due to glycosylation, IFN-ß has an approximate MW of 22.3 kDa based on SDS-PAGE gel
  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • beta-interferon
    • Fibroblast interferon
    • IFB
    • IFF
    • IFN beta
    • IFN-beta
    • IFNB
    • IFNB 1
    • IFNB_HUMAN
    • IFNB1
    • Interferon beta
    • Interferon beta 1 fibroblast
    • Interferon beta precursor
    • MGC96956
    see all
  • Function
    Has antiviral, antibacterial and anticancer activities.
  • Sequence similarities
    Belongs to the alpha/beta interferon family.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab71475 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Question
Answer

Thank you for contacting us. This protein does not contain any carrier protein.


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