Recombinant Human Jagged 2/JAG2 protein (ab114541)

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Description

  • Product name

    Recombinant Human Jagged 2/JAG2 protein

  • Expression system

    Wheat germ

  • Accession

    Q9Y219

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      AGGDQDPGLVVIPFQFAWPRSFTLIVEAWDWDNDTTPNEELLIERVSHAG MINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATCNKF

    • Predicted molecular weight

      36 kDa including tags

    • Amino acids

      121 to 210

Specifications

Our Abpromise guarantee covers the use of ab114541 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

    SDS-PAGE

  • Form

    Liquid

  • Additional notes

    This protein is best used within three months from the date of receipt.

    This product was previously labelled as Jagged 2.

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • D12Ggc2e
    • HJ 2
    • HJ2
    • JAG 2
    • JAG2
    • Jagged 2 precursor
    • Jagged2
    • Protein jagged 2
    • SER2
    • Syndactylism
    see all

  • Relevance

    Jagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.

  • Cellular localization

    Cell Membrane

Images

  • SDS-PAGE - Recombinant Human Jagged 2/JAG2 protein (ab114541)
    SDS-PAGE - Recombinant Human Jagged 2/JAG2 protein (ab114541)
    ab114541 on a 12.5% SDS-PAGE Stained with Coomassie Blue.

References

ab114541 has not yet been referenced specifically in any publications.

Publishing research using ab114541? Please let us know so that we can cite the reference in this datasheet.

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