Overview

  • Product name

    Recombinant Human JAML protein
  • Protein length

    Protein fragment

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Molecular weight

      26 kDa
    • Amino acids

      6 to 235
    • Tags

      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127608 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names

    • adhesion molecule AMICA
    • Adhesion molecule interacting with CXADR antigen 1
    • adhesion molecule interacts with CXADR antigen 1
    • adhesion molecule that interacts with CXADR antigen 1
    • AMICA
    • Amica1
    • CREA7-1
    • CREA7-4
    • Dendritic cell-specific protein CREA7-1
    • dendritic-cell specific protein CREA7-1
    • dendritic-cell specific protein CREA7-4
    • FLJ37080
    • Gm638
    • JAML1_HUMAN
    • junctional adhesion molecule
    • Junctional adhesion molecule-like
    • Junctional adhesion molecule-like precursor
    • MGC118814
    • MGC118815
    • UNQ722/PRO1387
    see all
  • Function

    May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.
  • Tissue specificity

    Expression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus.
  • Sequence similarities

    Belongs to the immunoglobulin superfamily.
    Contains 2 Ig-like V-type (immunoglobulin-like) domains.
  • Domain

    The Ig-like V-type domain 2 mediates interaction with CXADR.
  • Cellular localization

    Cell junction. Cell membrane. Localized at the plasma membrane in areas of cell-cell contacts and at the cell surface of PMN.
  • Information by UniProt

References

ab127608 has not yet been referenced specifically in any publications.

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