Recombinant Human JDP2 protein (ab156981)

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Overview

  • Product name

    Recombinant Human JDP2 protein

  • Protein length

    Full length protein

Description

  • Nature

    Recombinant

  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
      Q8WYK2

    • Species

      Human

    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSHMMPGQI PDPSVTTGSL PGLGPLTGLP SSALTVEELK YADIRNLGAM IAPLHFLEVK LGKRPQPVKS ELDEEEERRK RRREKNKVAA ARCRNKKKER TEFLQRESER LELMNAELKT QIEELKQERQ QLILMLNRHR PTCIVRTDSV KTPESEGNPL LEQLEKK

    • Molecular weight

      21 kDa including tags

    • Amino acids

      1 to 163

    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab156981 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF

  • Purity

    > 90 % SDS-PAGE.
    ab156981 purified using conventional chromatography techniques.

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Preservative: 1.7% Imidazole
    Constituents: 0.32% Tris HCl, 0.03% EDTA, 50% Glycerol, 1.17% Sodium chloride

General Info

  • Alternative names

    • Jdp2
    • JDP2_HUMAN
    • Jun dimerization protein 2
    • JUNDM2
    • Progesterone receptor co-activator
    see all

  • Function

    Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.

  • Sequence similarities

    Belongs to the bZIP family. ATF subfamily.
    Contains 1 bZIP domain.

  • Post-translational
    modifications

    Phosphorylation of Thr-148 by MAPK8 in response to different stress conditions such as, UV irradiation, oxidatives stress and anisomycin treatments.

  • Cellular localization

    Nucleus.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human JDP2 protein (ab156981)
    SDS-PAGE - Recombinant Human JDP2 protein (ab156981)
    15% SDS-PAGE analysis of ab156981 (3µg).

References

ab156981 has not yet been referenced specifically in any publications.

Publishing research using ab156981? Please let us know so that we can cite the reference in this datasheet.

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