Recombinant Human JDP2 protein (ab156981)

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SDS-PAGE - Recombinant Human JDP2 protein (ab156981)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 90% SDS-PAGE
    • Tags: His tag N-Terminus
    • Suitable for: SDS-PAGE, MS

    Description

    • Product name

      Recombinant Human JDP2 protein

    • Purity

      > 90 % SDS-PAGE.
      ab156981 purified using conventional chromatography techniques.

    • Expression system

      Escherichia coli

    • Accession

      Q8WYK2

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MGSSHHHHHH SSGLVPRGSH MGSHMMPGQI PDPSVTTGSL PGLGPLTGLP SSALTVEELK YADIRNLGAM IAPLHFLEVK LGKRPQPVKS ELDEEEERRK RRREKNKVAA ARCRNKKKER TEFLQRESER LELMNAELKT QIEELKQERQ QLILMLNRHR PTCIVRTDSV KTPESEGNPL LEQLEKK

      • Predicted molecular weight

        21 kDa including tags

      • Amino acids

        1 to 163

      • Tags

        His tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab156981 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      Mass Spectrometry

    • Mass spectrometry

      MALDI-TOF

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 8.00
      Preservative: 1.7% Imidazole
      Constituents: 0.32% Tris HCl, 0.03% EDTA, 50% Glycerol (glycerin, glycerine), 1.17% Sodium chloride, 0.02% DTT

    General Info

    • Alternative names

      • Jdp2
      • JDP2_HUMAN
      • Jun dimerization protein 2
      • JUNDM2
      • Progesterone receptor co-activator
      see all

    • Function

      Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.

    • Sequence similarities

      Belongs to the bZIP family. ATF subfamily.
      Contains 1 bZIP domain.

    • Post-translational
      modifications

      Phosphorylation of Thr-148 by MAPK8 in response to different stress conditions such as, UV irradiation, oxidatives stress and anisomycin treatments.

    • Cellular localization

      Nucleus.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human JDP2 protein (ab156981)
      SDS-PAGE - Recombinant Human JDP2 protein (ab156981)
      15% SDS-PAGE analysis of ab156981 (3µg).

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab156981? Please let us know so that we can cite the reference in this datasheet.

    ab156981 has not yet been referenced specifically in any publications.

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