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Recombinant Human Junctional Adhesion Molecule 1/JAM-A protein (ab126670)

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SDS-PAGE - Recombinant Human Junctional Adhesion Molecule 1/JAM-A protein (ab126670)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 90% SDS-PAGE
    • Tags: His tag N-Terminus
    • Suitable for: SDS-PAGE, MS

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    Description

    • Product name

      Recombinant Human Junctional Adhesion Molecule 1/JAM-A protein
      See all Junctional Adhesion Molecule 1/JAM-A proteins and peptides
    • Purity

      > 90 % SDS-PAGE.
      ab126670 was purified using conventional chromatography.
    • Expression system

      Escherichia coli
    • Accession

      Q9Y624
    • Protein length

      Protein fragment
    • Animal free

      No
    • Nature

      Recombinant
      • Species

        Human
      • Sequence

        MGSSHHHHHH SSGLVPRGSH MGSHMLGSVT VHSSEPEVRI PENNPVKLSC AYSGFSSPRV EWKFDQGDTT RLVCYNNKIT ASYEDRVTFL PTGITFKSVT REDTGTYTCM VSEEGGNSYG EVKVKLIVLV PPSKPTVNIP SSATIGNRAV LTCSEQDGSP PSEYTWFKDG IVMPTNPKST RAFSNSSYVL NPTTGELVFD PLSASDTGEY SCEARNGYGT PMTSNAVRME AVERNVGV
      • Predicted molecular weight

        26 kDa including tags
      • Amino acids

        26 to 238
      • Tags

        His tag N-Terminus

    Associated products

    • Related Products

      • Anti-6X His tag® antibody [HIS.H8] (ab18184)
      • Anti-6X His tag® antibody [4D11] (ab5000)

    Specifications

    Our Abpromise guarantee covers the use of ab126670 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      Mass Spectrometry

    • Mass spectrometry

      MALDI-TOF
    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 8.00
      Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol (glycerin, glycerine), 0.88% Sodium chloride

    General Info

    • Alternative names

      • CD 321
      • CD321
      • CD321 antigen
      • ESTM33
      • F11 receptor
      • F11R
      • JAM
      • JAM 1
      • JAM A
      • JAM-1
      • JAM-A
      • JAM1
      • JAM1_HUMAN
      • JAMA
      • JCAM
      • Jcam1
      • Junction adhesion molecule 1
      • Junction adhesion molecule, mouse, homolog of
      • Junctional adhesion molecule 1
      • Junctional adhesion molecule A
      • KAT
      • Ly106
      • PAM 1
      • PAM-1
      • PAM1
      • Platelet adhesion molecule
      • Platelet adhesion molecule 1
      • Platelet F11 receptor
      • PRO301
      • UNQ264
      see all
    • Function

      Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.
    • Sequence similarities

      Belongs to the immunoglobulin superfamily.
      Contains 2 Ig-like V-type (immunoglobulin-like) domains.
    • Post-translational
      modifications

      N-glycosylated.
    • Cellular localization

      Cell junction > tight junction. Cell membrane. Localized at tight junctions of both epithelial and endothelial cells.
    • Target information above from: UniProt accession Q9Y624 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human Junctional Adhesion Molecule 1/JAM-A protein (ab126670)
      SDS-PAGE - Recombinant Human Junctional Adhesion Molecule 1/JAM-A protein (ab126670)
      15% SDS-PAGE analysis of ab126670 (3µg)

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
    • SDS
  • References (0)

    Publishing research using ab126670? Please let us know so that we can cite the reference in this datasheet.

    ab126670 has not yet been referenced specifically in any publications.

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