Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHHSSGLVPRGSHMGSLGYHKAYGFSAPKDQQVVTAVEYQEAI LACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIK NVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALS GTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTG TLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNIS
    • Molecular weight

      27 kDa including tags
    • Amino acids

      21 to 238
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab139237 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity

    > 90 % SDS-PAGE.

  • Form

    Liquid
  • Additional notes

    Previously labelled as Junctional Adhesion Molecule 2.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 2.4% Urea, 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names

    • C21orf43
    • CD 322
    • CD322
    • CD322 antigen
    • JAM 2
    • JAM B
    • JAM IT/VE JAM
    • JAM, vascular endothelial
    • JAM-2
    • JAM-B
    • JAM2
    • JAM2_HUMAN
    • JAMB
    • Jcam2
    • Junction adhesion molecule 2
    • Junction adhesion molecule B
    • Junctional adhesion molecule 2
    • Junctional adhesion molecule B
    • PRO 245
    • PRO245
    • Vascular endothelial junction associated molecule
    • Vascular endothelial junction-associated molecule
    • VE JAM
    • VE-JAM
    • VEJAM
    see all
  • Function

    May play a role in the processes of lymphocyte homing to secondary lymphoid organs.
  • Tissue specificity

    Highest expression in the heart, placenta, lung, foreskin and lymph node. Prominently expressed on high endothelial venules, also present on the endothelia of other vessels. Localized to the intercellular boundaries of high endothelial cells.
  • Sequence similarities

    Belongs to the immunoglobulin superfamily.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization

    Cell junction > tight junction. Cell membrane. Localized at tight junctions of both epithelial and endothelial cells.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of 3 µg ab139237.

References

ab139237 has not yet been referenced specifically in any publications.

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