Recombinant Human KCTD5 protein (ab137135)

Submit a review Submit a question

Description

  • Product name

    Recombinant Human KCTD5 protein

  • Purity

    > 90 % SDS-PAGE.
    ab137135 was purified using conventional chromatography techniques.

  • Expression system

    Escherichia coli

  • Accession

    Q9NXV2

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MGSSHHHHHHSSGLVPRGSHMGSMAENHCELLSPARGGIGAGLGGGLCRR CSAGLGALAQRPGSVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQAD PDLDSDKDETGAYLIDRDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAE FYNITSLIKLVKDKIRERDSKTSQVPVKHVYRVLQCQEEELTQMVSTMSD GWKFEQLVSIGSSYNYGNEDQAEFLCVVSKELHNTPYGTASEPSEKAKIL QERGSRM

    • Predicted molecular weight

      29 kDa including tags

    • Amino acids

      1 to 234

    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab137135 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 40% Glycerol, 1.17% Sodium chloride

General Info

  • Alternative names

    • BTB/POZ domain-containing protein KCTD5
    • FLJ20040
    • KCTD5
    • KCTD5_HUMAN
    • Potassium channel tetramerisation domain containing 5
    see all

  • Function

    Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex. Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4.

  • Sequence similarities

    Contains 1 BTB (POZ) domain.

  • Domain

    The BTB (POZ) domain is atypical and mediates the formation of a homopentamer instead of a homotetramer. Homopentamerization is due to the presence of 4 residues in the BTB (POZ) domain: Leu-56, Gly-100, Val-112 and Ala-118.

  • Cellular localization

    Cytoplasm > cytosol. Nucleus. Predominantly cytoplasmic, translocated to the nucleus upon interaction with Rep proteins.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human KCTD5 protein (ab137135)
    SDS-PAGE - Recombinant Human KCTD5 protein (ab137135)
    15% SDS-PAGE analysis of 3 µg ab137135.

References

ab137135 has not yet been referenced specifically in any publications.

Publishing research using ab137135? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

Show All Reviews Q&A
Submit a review Submit a question

There are currently no Customer reviews or Questions for ab137135.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com