Recombinant Human KCTD5 protein (ab137135)

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SDS-PAGE - Recombinant Human KCTD5 protein (ab137135)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 90% SDS-PAGE
    • Tags: His tag N-Terminus
    • Suitable for: SDS-PAGE, MS

    Description

    • Product name

      Recombinant Human KCTD5 protein

    • Purity

      > 90 % SDS-PAGE.
      ab137135 was purified using conventional chromatography techniques.

    • Expression system

      Escherichia coli

    • Accession

      Q9NXV2

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MGSSHHHHHHSSGLVPRGSHMGSMAENHCELLSPARGGIGAGLGGGLCRR CSAGLGALAQRPGSVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQAD PDLDSDKDETGAYLIDRDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAE FYNITSLIKLVKDKIRERDSKTSQVPVKHVYRVLQCQEEELTQMVSTMSD GWKFEQLVSIGSSYNYGNEDQAEFLCVVSKELHNTPYGTASEPSEKAKIL QERGSRM

      • Predicted molecular weight

        29 kDa including tags

      • Amino acids

        1 to 234

      • Tags

        His tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab137135 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      Mass Spectrometry

    • Mass spectrometry

      MALDI-TOF

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 8.00
      Constituents: 0.02% DTT, 0.32% Tris HCl, 40% Glycerol (glycerin, glycerine), 1.17% Sodium chloride

    General Info

    • Alternative names

      • BTB/POZ domain-containing protein KCTD5
      • FLJ20040
      • KCTD5
      • KCTD5_HUMAN
      • Potassium channel tetramerisation domain containing 5
      see all

    • Function

      Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex. Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4.

    • Sequence similarities

      Contains 1 BTB (POZ) domain.

    • Domain

      The BTB (POZ) domain is atypical and mediates the formation of a homopentamer instead of a homotetramer. Homopentamerization is due to the presence of 4 residues in the BTB (POZ) domain: Leu-56, Gly-100, Val-112 and Ala-118.

    • Cellular localization

      Cytoplasm > cytosol. Nucleus. Predominantly cytoplasmic, translocated to the nucleus upon interaction with Rep proteins.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human KCTD5 protein (ab137135)
      SDS-PAGE - Recombinant Human KCTD5 protein (ab137135)
      15% SDS-PAGE analysis of 3 µg ab137135.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab137135? Please let us know so that we can cite the reference in this datasheet.

    ab137135 has not yet been referenced specifically in any publications.

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