Overview

  • Product name

    Recombinant Human KCTD8 protein
  • Protein length

    Protein fragment

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Molecular weight

      18 kDa
    • Amino acids

      208 to 364
    • Tags

      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127631 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity

    > 95 % Purified via His tag.
    Purity was determined to be >95% by SDS-PAGE.
  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names

    • BTB/POZ domain-containing protein KCTD8
    • KCTD8
    • KCTD8_HUMAN
    • Potassium channel tetramerisation domain containing 8
  • Function

    Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
  • Sequence similarities

    Contains 1 BTB (POZ) domain.
  • Cellular localization

    Cell junction > synapse > presynaptic cell membrane. Cell junction > synapse > postsynaptic cell membrane.
  • Information by UniProt

References

ab127631 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab127631.
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