Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: SDS-PAGE, ELISA, WB
Product nameRecombinant Human KDM6A / UTX protein
See all KDM6A / UTX proteins and peptides
Expression systemWheat germ
Protein lengthProtein fragment
Amino acids641 to 740
TagsGST tag N-Terminus
Our Abpromise guarantee covers the use of ab159790 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.31% Glutathione, 0.79% Tris HCl
- bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX)
- bA386N14.2 ubiquitously transcribed X chromosome tetratricopeptide repeat protein UTX
FunctionHistone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitent with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
Sequence similaritiesBelongs to the UTX family.
Contains 1 JmjC domain.
Contains 8 TPR repeats.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab159790 has not yet been referenced specifically in any publications.