Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MCNDMTPEQM ATNVNCSSPE RHTRSYDYME GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MKNNYNIMEI RTVAVGIVAI KGVESEFYLA MNKEGKLYAK KECNEDCNFK ELILENHYNT YASAKWTHNG GEMFVALNQK GIPVRGKKTK KEQKTAHFLP MAIT
    • Molecular weight

      19 kDa
    • Amino acids

      32 to 194
    • Additional sequence information

      Mature protein without signal peptide.

Associated products

Specifications

Our Abpromise guarantee covers the use of ab218091 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity

    The activity is determined by the dose-dependent proliferation of 4MBr5 cells and is typically 2-3 ng/mL. This corresponds to an expected specific activity of 5 x 105 units/mg.

  • Applications

    SDS-PAGE

    Functional Studies

  • Endotoxin level

    < 0.050 Eu/µg
  • Purity

    > 90 % SDS-PAGE.
    Purity of ab218091 is typically 90% as determined by reducing and non-reducing SDS-PAGE.
  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon reconsitution add a carrier protein (0.1% BSA). Store at -20°C or -80°C. Avoid freeze / thaw cycle. Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C..

    pH: 7.5
    Constituents: 0.08% Sodium phosphate, 0.87% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Reconstitute in sterile water at 0.1 mg/mL. Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store in a manual defrost freezer at -80 ºC and avoid repeat freeze thaws.

General Info

  • Alternative names

    • FGF 7
    • FGF-7
    • Fgf7
    • FGF7_HUMAN
    • Fibroblast growth factor 7
    • HBGF 7
    • HBGF-7
    • HBGF7
    • Heparin binding growth factor 7
    • Heparin-binding growth factor 7
    • Keratinocyte growth factor
    • KGF
    see all
  • Function

    Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation.
  • Tissue specificity

    Epithelial cell.
  • Sequence similarities

    Belongs to the heparin-binding growth factors family.
  • Cellular localization

    Secreted.
  • Information by UniProt

References

ab218091 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab218091.
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