Description

  • Product name

    Recombinant Human KIAA0652/ATG13 protein
  • Purity

    > 70 % Densitometry.

  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Predicted molecular weight

      96 kDa including tags
    • Amino acids

      1 to 517

Associated products

Specifications

Our Abpromise guarantee covers the use of ab127606 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

  • Form

    Liquid
  • Additional notes

     This product was previously labelled as KIAA0652

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.29% Sodium chloride

General Info

  • Alternative names

    • ATG13
    • ATG13 autophagy related 13 homolog (S. cerevisiae)
    • ATG13_HUMAN
    • Autophagy related 13
    • Autophagy related protein 13
    • Autophagy-related protein 13
    • FLJ20698
    • KIAA0652
    • OTTHUMP00000233321
    • OTTHUMP00000233322
    • OTTHUMP00000233323
    • OTTHUMP00000233324
    • OTTHUMP00000233325
    • OTTHUMP00000233326
    see all
  • Function

    Autophagy factor required for autophagosome formation. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex.
  • Sequence similarities

    Belongs to the ATG13 metazoan family.
  • Post-translational
    modifications

    Phosphorylated by ULK1 and ULK2. Phosphorylation status depends on nutrient-rich conditions; dephosphorylated during starvation or following treatment with rapamycin.
  • Cellular localization

    Cytoplasm > cytosol. Preautophagosomal structure. Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane and the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation.
  • Information by UniProt

Images

  • SDS-PAGE analysis of ab127606.

References

ab127606 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab127606.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up