Description

  • Product name

    Recombinant Human KIBRA protein
  • Purity

    > 90 % SDS-PAGE.
    ab177657 was purified using conventional chromatography techniques.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSEAVGATR IQIALKYDEK NKQFAILIIQ LSNLSALLQQ QDQKVNIRVA VLPCSESTTC LFRTRPLDASDTLVFNEVFW VSMSYPALHQ KTLRVDVCTT DRSHLEECLG GAQISLAEVC RSGERSTRWY NL
    • Predicted molecular weight

      17 kDa including tags
    • Amino acids

      655 to 783
    • Tags

      His tag N-Terminus
    • Additional sequence information

      C2 domain. (NP_056053).

Specifications

Our Abpromise guarantee covers the use of ab177657 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Information available upon request.

General Info

  • Alternative names

    • FLJ10865
    • FLJ23369
    • HBeAg-binding protein 3
    • HBEBP3
    • HBEBP36
    • KIAA0869
    • KIBRA
    • Kidney and brain protein
    • Protein KIBRA
    • Protein WWC1
    • WW and C2 domain containing 1
    • WW C2 and coiled-coil domain containing 1
    • WW domain-containing protein 1
    • WWC1
    see all
  • Relevance

    KIBRA is a WW domain containing protein, first identified by yeast 2-hybrid analysis of a human brain cDNA expression library. Gene expression studies have shown that KIBRA is expressed in memory-related brain structures including the hippocampus (dentate gyrus and the CA1 region) and the temporal lobe, 2 key regions for memory, and that the expression of specific KIBRA alleles is significantly associated with memory performance.
  • Cellular localization

    Cytoplasm. Cytoplasm › perinuclear region. Nucleus. Cell projection › ruffle membrane. Note: Co-localizes with PRKCZ in the perinuclear region.

Images

  • 15% SDS-PAGE analysis of ab177657 (3 µg).

References

ab177657 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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