The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
>90% by SDS-PAGE. The final product was refolded using a unique “temperature shift inclusion body refolding” technology and chromatographically purified.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituent: 0.32% Tris HCl Note: Contains NaCl, KCl, EDTA, arginine, DTT and Glycerol.
CUL3 interacting protein 1
CUL3-interacting protein 1
Kelch like 12
Kelch like 12 (Drosophila)
Kelch like 12 variant
Kelch like protein 12
Kelch like protein C3IP1
kelch-like family member 12
Kelch-like protein 12
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
Highly expressed in testis and at lower levels in the submandibular salivary gland.