Overview

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Species

      Human
    • Sequence

      MEGESVKLSSQTLIQAGDDEKNQRTITVNPAHMGKAFKVMNELRSKQLLC DVMIVAEDVEIEAHR
    • Amino acids

      1 to 65
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab153272 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • FLJ40871
    • kelch (Drosophila) like 3
    • kelch like 3
    • kelch like 3 (Drosophila)
    • Kelch like protein 3
    • KIAA1129
    • KLHL 3
    • KLHL3
    • MGC44594
    see all
  • Relevance

    KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77% similarity with Drosophila kelch and 89% similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q; however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.
  • Cellular localization

    Cytoplasmic and cytoskeleton.

Images

  • ab153272 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab153272 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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