Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 85% SDS-PAGE
- Suitable for: SDS-PAGE, WB
Product nameRecombinant Human KMT3C / SMYD2 protein
See all KMT3C / SMYD2 proteins and peptides
Purity> 85 % SDS-PAGE.
The purity was determined to be >85% by densitometry
Expression systemBaculovirus infected Sf9 cells
Protein lengthFull length protein
Predicted molecular weight70 kDa including tags
Amino acids1 to 371
Our Abpromise guarantee covers the use of ab107699 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.307% Glutathione, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol, 0.29% Sodium chloride
- Histone methyltransferase SMYD2
- HSKM B
FunctionProtein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates 'Lys-860' of RB1/RB.
Sequence similaritiesContains 1 MYND-type zinc finger.
Contains 1 SET domain.
Cellular localizationCytoplasm > cytosol. Nucleus.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab107699 has not yet been referenced specifically in any publications.