The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 µg/µl.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Voltage gated K+ channel HuKII
Fetal skeletal muscle potassium channel
Potassium channel 2
Potassium voltage gated channel shaker related subfamily member 4
Potassium voltage gated channel subfamily A member 4
Potassium voltage-gated channel subfamily A member 4
Rapidly inactivating potassium channel
Shaker related potassium channel Kv1.4
Type A potassium channel
Voltage gated potassium channel HBK4
Voltage gated potassium channel HK1
Voltage gated potassium channel subunit Kv1.4
Voltage-gated K(+) channel HuKII
Voltage-gated potassium channel HBK4
Voltage-gated potassium channel HK1
Voltage-gated potassium channel subunit Kv1.4
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments. The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.