Description

  • Product name

    Recombinant Human LARP7 protein
  • Expression system

    Wheat germ
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      METESGNQEKVMEEESTEKKKEVEKKETVTS
    • Amino acids

      1 to 31
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab162597 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • DKFZp564K112
    • HDCMA18P
    • La related protein 7
    • La ribonucleoprotein domain family member 7
    • La ribonucleoprotein domain family member 7
    • La-related protein 7
    • LARP 7
    • larp7
    • LARP7_HUMAN
    • MGC104360
    • P TEFb interaction protein for 7SK stability
    • P-TEFb-interaction protein for 7SK stability
    • PIP7S
    see all
  • Function

    Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
  • Sequence similarities

    Contains 1 HTH La-type RNA-binding domain.
    Contains 1 RRM (RNA recognition motif) domain.
  • Post-translational
    modifications

    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization

    Nucleus > nucleoplasm.
  • Information by UniProt

Images

  • ab162597 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab162597 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab162597.
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