Recombinant Human LAT3 protein (ab160057)

Our Abpromise guarantee covers the use of ab160057 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Alternative names
- L type amino acid transporter 3
- L-type amino acid transporter 3
- Large neutral amino acids transporter small subunit 3
- LAT3_HUMAN
- PB39
- POV1
- Prostate cancer overexpressed gene 1 protein
- R00504
- SLC43A1
- Solute carrier family 43 member 1
see all
Function

Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.
Tissue specificity

In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.
Sequence similarities

Belongs to the SLC43A transporter (TC 2.A.1.44) family.
Cellular localization

Membrane.
Target information above from: UniProt accession O75387 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

SDS-PAGE - Recombinant Human LAT3 protein (ab160057)

ab160057 on a 12.5% SDS-PAGE stained with Coomassie Blue.

ab160057 has not yet been referenced specifically in any publications.

Publishing research using ab160057? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"