Recombinant Human LEFTY2 protein (His tag) (ab215580)
Key features and details
- Expression system: Mammalian
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
Description
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Product name
Recombinant Human LEFTY2 protein (His tag)
See all LEFTY2 proteins and peptides -
Purity
> 95 % SDS-PAGE. -
Endotoxin level
< 1.000 Eu/µg -
Expression system
Mammalian -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
HHHHHHFSQSFREVAGRFLASEASTHLLVFGMEQRLPPNSELVQAVLRLF QEPVPKAALHRHGRLSPRSAQARVTVEWLRVRDDGSNRTSLIDSRLVSVH ESGWKAFDVTEAVNFWQQLSRPRQPLLLQVSVQREHLGPLASGAHKLVRF ASQGAPAGLGEPQLELHTLDLRDYGAQGDCDPEAPMTEGTRCCRQEMYID LQGMKWAKNWVLEPPGFLAYECVGTCQQPPEALAFNWPFLGPRQCIASET ASLPMIVSIKEGGRTRPQVVSLPNMRVQKCSCASDGALVPRRLQP -
Predicted molecular weight
33 kDa including tags -
Amino acids
78 to 366 -
Tags
His tag N-Terminus -
Additional sequence information
Full length mature chain without signal peptide, without propeptide.
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab215580 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20°C or -80°C.
pH: 7.40
Constituent: PBS -
ReconstitutionReconstitute with ddH2O to a concentration no less than 100 µg/mL.Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
General Info
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Alternative names
- EBAF
- Endometrial bleeding associated factor
- Endometrial bleeding associated factor (left right determination factor A transforming growth factor beta superfamily)
see all -
Function
Required for left-right (L-R) asymmetry determination of organ systems in mammals. May play a role in endometrial bleeding. -
Tissue specificity
Mesenchymal cells of the endometrial stroma. -
Involvement in disease
Defects in LEFTY2 are the cause of left-right axis malformations (LRAM) [MIM:601877]. The defect includes left pulmonary isomerism, with cardiac anomalies characterized by complete atrioventricular canal defect and hypoplastic left ventricle, and interrupted inferior vena cava. -
Sequence similarities
Belongs to the TGF-beta family. -
Developmental stage
Transiently expressed before and during menstrual bleeding. -
Post-translational
modificationsThe processing of the protein may also occur at the second R-X-X-R site located at AA 132-135. Processing appears to be regulated in a cell-type specific manner. -
Cellular localization
Secreted. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab215580 has not yet been referenced specifically in any publications.