Overview

  • Product name

    Recombinant Human LEPREL1 protein
  • Protein length

    Protein fragment

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Molecular weight

      20 kDa
    • Amino acids

      233 to 399
    • Tags

      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127622 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names

    • 4832416N06
    • AW553532
    • Leprecan like 1
    • Leprecan-like protein 1
    • Leprel1
    • MCVD
    • MLAT4
    • Myxoid liposarcoma-associated protein 4
    • P3H2
    • P3H2_HUMAN
    • Prolyl 3 hydroxylase 3
    • Prolyl 3-hydroxylase 2
    see all
  • Function

    Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly-sequences in collagens, especially types IV and V.
  • Tissue specificity

    Expressed in heart, placenta, lung, liver, skeletal muscle and kidney. Expression localized to the epithelia of bile ducts and to the sacroplasm of heart muscle and skeletal muscle. In the pancreas, localized to a subpopulation of Langerhans islet cells and in the salivary gland, expressed in acinar cells.
  • Sequence similarities

    Belongs to the leprecan family.
    Contains 1 Fe2OG dioxygenase domain.
    Contains 4 TPR repeats.
  • Cellular localization

    Endoplasmic reticulum. Golgi apparatus.
  • Information by UniProt

References

ab127622 has not yet been referenced specifically in any publications.

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