Description

  • Product name

    Recombinant Human LIGHT/TNFSF14 protein
    See all LIGHT/TNFSF14 proteins and peptides
  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

    < 0.100 Eu/µg
  • Expression system

    CHO cells
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Predicted molecular weight

      25 kDa including tags
    • Amino acids

      89 to 240
    • Tags

      DDDDK tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab109159 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Additional notes

     This product was previously labelled as LIGHT

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

    Constituent: PBS

  • Reconstitution
    Reconstitute with 100 µl sterile water. PBS containing at least 0.1% BSA should be used for further dilutions.

General Info

  • Alternative names

    • CD 258
    • CD258
    • CD258 antigen
    • Delta transmembrane LIGHT
    • Herpes virus entry mediator ligand
    • Herpesvirus entry mediator A
    • Herpesvirus entry mediator ligand
    • herpesvirus entry mediator-ligand
    • HVEM L
    • HVEM-L
    • HVEML
    • Ligand for herpesvirus entry mediator
    • LIGHT
    • LTg
    • soluble form
    • TNF14
    • TNF14_HUMAN
    • TNFSF 14
    • Tnfsf14
    • TNFSF14 protein
    • TR 2
    • TR2
    • Tumor necrosis factor (ligand) superfamily, member 14
    • Tumor necrosis factor ligand superfamily member 14
    • Tumor necrosis factor ligand superfamily, member 14
    • Tumor necrosis factor receptor like 2
    • tumor necrosis factor receptor-like 2
    • Tumor necrosis factor superfamily member 14
    • Tumor necrosis factor superfamily member LIGHT
    see all
  • Function

    Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
  • Tissue specificity

    Predominantly expressed in the spleen but also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumor lines.
  • Sequence similarities

    Belongs to the tumor necrosis factor family.
  • Post-translational
    modifications

    N-glycosylated.
    The soluble form of isoform 1 derives from the membrane form by proteolytic processing.
  • Cellular localization

    Cytoplasm; Secreted and Cell membrane.
  • Information by UniProt

References

ab109159 has not yet been referenced specifically in any publications.

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