Recombinant Human LILRB5 protein (His tag) (ab219882)

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Description

  • Product name

    Recombinant Human LILRB5 protein (His tag)

  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

    < 1.000 Eu/µg

  • Expression system

    HEK 293 cells

  • Accession

    O75023

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      GTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQN PLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGFYAE PTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPK GPSQALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRK PSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQA GLSQANFTLGPVSRSHGGQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDI PALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQS YRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGD PSLSPTGSTPTPGPEDQPLTPTGLDPQSGLGRHLG

    • Predicted molecular weight

      49 kDa including tags

    • Amino acids

      24 to 458

    • Tags

      His tag C-Terminus

    • Additional sequence information

      Extracellular domain (NP_006831).

Specifications

Our Abpromise guarantee covers the use of ab219882 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 95% PBS, 5% Trehalose

    Lyophilized from 0.22 µm filtered solution.

  • Reconstitution
    It is recommended to reconstitute the lyophilized protein in sterile deionized water to a final concentration of 1mg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage.

General Info

  • Alternative names

    • CD85 antigen-like family member C
    • CD85c
    • Leukocyte immunoglobulin-like receptor 8
    • Leukocyte immunoglobulin-like receptor subfamily B member 5
    • LILRB5
    • LIR-8
    • LIR8
    • LIRB5_HUMAN
    see all

  • Function

    May act as receptor for class I MHC antigens.

  • Tissue specificity

    Detected in a natural killer (NK) cells.

  • Sequence similarities

    Contains 4 Ig-like C2-type (immunoglobulin-like) domains.

  • Domain

    Contains 2 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.

  • Cellular localization

    Membrane.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human LILRB5 protein (His tag) (ab219882)
    SDS-PAGE - Recombinant Human LILRB5 protein (His tag) (ab219882)

    SDS-PAGE analysis of reduced ab219882 stained overnight with Coomassie Blue.

    The protein migrates as 66-68 kDa under reducing conditions (SDS-PAGE) due to glycosylation.

References

ab219882 has not yet been referenced specifically in any publications.

Publishing research using ab219882? Please let us know so that we can cite the reference in this datasheet.

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