Description

  • Product name

    Recombinant human LIMPII protein
    See all LIMPII proteins and peptides
  • Biological activity

    Measured by its binding ability in a functional ELISA.

    Immobilized ab191655 at 5 µg/ml (100 µl/well) can bind rhTSP-2/His with a linear range of 0.1 - 5 µg/ml.

  • Purity

    > 95 % SDS-PAGE.
    Lyophilized from 0.22 µm filtered solution
  • Endotoxin level

    < 1.000 Eu/µg
  • Expression system

    HEK 293 cells
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      RVFQ KAVDQSIEKK IVLRNGTEAF DSWEKPPLPV YTQFYFFNVT NPEEILRGET PRVEEVGPYT YRELRNKANI QFGDNGTTIS AVSNKAYVFE RDQSVGDPKI DLIRTLNIPV LTVIEWSQVH FLREIIEAML KAYQQKLFVT HTVDELLWGY KDEILSLIHV FRPDISPYFG LFYEKNGTND GDYVFLTGED SYLNFTKIVE WNGKTSLDWW ITDKCNMING TDGDSFHPLI TKDEVLYVFP SDFCRSVYIT FSDYESVQGL PAFRYKVPAE ILANTSDNAG FCIPEGNCLG SGVLNVSICK NGAPIIMSFP HFYQADERFV SAIEGMHPNQ EDHETFVDIN PLTGIILKAA KRFQINIYVK KLDDFVETGD IRTMVFPVMY LNESVHIDKE TASRLKSMIN TT
    • Predicted molecular weight

      73 kDa including tags
    • Amino acids

      27 to 432
    • Additional sequence information

      Lumenal domain fused with Fc fragment of human IgG1 at the C-terminus.

Associated products

Specifications

Our Abpromise guarantee covers the use of ab191655 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at 4°C prior to reconstitution. Store at +4°C. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA).

    pH: 7.50
    Constituents: 0.61% Tris, 0.75% Glycine

    5-10% trehalose is commonly used for freeze drying, and after reconstitution, the trehalose is mostly about 3-5%

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Reconstitute in 100 µl sterile deionized water to a final concentration of 1 mg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage.

General Info

  • Alternative names

    • 85 kDa lysosomal membrane sialoglycoprotein
    • 85 kDa lysosomal sialoglycoprotein scavenger receptor class B member 2
    • AMRF
    • CD36
    • CD36 antigen
    • CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II)
    • CD36 antigen-like 2
    • CD36L2
    • EPM4
    • HLGP85
    • LGP85
    • LIMP 2
    • LIMP II
    • LIMP2
    • LIMPII
    • Lysosomal integral membrane protein II
    • Lysosome membrane protein 2
    • Lysosome membrane protein II
    • OTTHUMP00000160590
    • OTTHUMP00000219176
    • Scarb2
    • Scavenger receptor class B member 2
    • Scavenger receptor class B, member 2
    • SCRB2_HUMAN
    • SR BII
    • SRBII
    see all
  • Function

    Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting.
    (Microbial infection) Acts as a receptor for enterovirus 71.
  • Involvement in disease

    Epilepsy, progressive myoclonic 4, with or without renal failure
    Genetic variants in SCARB2 can act as modifier of the phenotypic expression and severity of Gaucher disease.
  • Sequence similarities

    Belongs to the CD36 family.
  • Cellular localization

    Lysosome membrane.
  • Information by UniProt

Images

  • SDS Page analysis of ab191655. DTT-reduced Protein migrates as 90-115 kDa due to glycosylation.

References

ab191655 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab191655.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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