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Full length protein
Recombinant Human LMX1b protein
Amino Acid Sequence
MGSSHHHHHHSSGLVPRGSHMGSMDIATGPESLERCFPRGQTDCAKMLDG IKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWH EECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEF VMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLS SVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILT TQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKL ARRHQQQQEQQNSQRLGQEVLSSRMEGMMASYTPLAPPQQQIVAMEQSPY GSSDPFQQGLTPPQMPGNDSIFHDIDSDTSLTSLSDCFLGSSDVGSLQAR VGNPIDRLYSMQSSYFAS
47 kDa including tags
1 to 395
His tag N-Terminus
Additional sequence information
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Constituents: 0.32% Tris HCl, 10% Glycerol, 2.4% Urea
- LIM homeo box transcription factor 1 beta
- LIM homeobox transcription factor 1 beta
- LIM homeobox transcription factor 1-beta
Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels.
Expressed in most tissues. Highest levels in testis, thyroid, duodenum, skeletal muscle, and pancreatic islets.
Involvement in disease
Defects in LMX1B are the cause of nail-patella syndrome (NPS) [MIM:161200]; also known as onychoosteodysplasia. NPS is a disease that cause abnormal skeletal patterning and renal dysplasia.
Contains 1 homeobox DNA-binding domain.
Contains 2 LIM zinc-binding domains.
Information by UniProt
SDS-PAGE - Human LMX1b full length protein (ab181911)
15% SDS-PAGE analysis of ab181911 (3µg).
has not yet been referenced specifically in any publications.
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