Description

  • Product name

    Recombinant Human LRRC17 protein
  • Expression system

    Wheat germ
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      RKASPGSVRSRVNHGRAGGGRRGSNPVKRYAPGLPCDVYTYLHEKYLDCQ ERKLVYVLPGWPQDLLHMLLARNKIRTLKNNMFSKFKKLKSLDLQQNEIS KIESEAFFGLNKLTTLLLQHNQIKVLTEEVFIYTPLLSYLRLYDNPWHCT CEIETLISMLQIPRNRNLGNYAKCESPQEQKNKKLRQIKSEQLCNEEEKE QLDPKPQVSGRPPVIKPEVDSTFCHNYVFPIQTLDCKRKELKKVPNNIPP DIVKLDLSYNKINQLRPKEFEDVHELKKLNLSSNGIEFIDPAAFLGLTHL EELDLSNNSLQNFDYGVLEDLYFLKLLWLRDNPWRCDYNIHYLYYWLKHH YNVHFNGLECKTPEEYKGWSVGKYIRSYYEECPKDKLPAYPESFDQDTED DEWEKKHRDHTAKKQSVIITIVG
    • Amino acids

      19 to 441
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab160894 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • 37 kDa leucine rich repeat (LRR) protein
    • 37kDa
    • 4833425M04Rik
    • 6130400C22Rik
    • Leucine-rich repeat-containing protein 17
    • LRC17_HUMAN
    • LRRC17
    • p37NB
    • UNQ3076/PRO9909
    see all
  • Function

    Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors.
  • Tissue specificity

    Expressed in osteoblast cell lines. Well expressed in ovary, heart, pancreas, skeletal muscle, lung, and fetal kidney and lung and only at the basal levels in the other tissues examined including adult kidney. More expressed in S-type neuroblastoma cells than in N-type neuroblastoma cells.
  • Sequence similarities

    Contains 6 LRR (leucine-rich) repeats.
    Contains 2 LRRCT domains.
    Contains 1 LRRNT domain.
  • Cellular localization

    Secreted > extracellular space.
  • Information by UniProt

Images

  • ab160894 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab160894 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab160894.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up